Investigation of the Role of the Microbiome in the Pathogenesis of Colorectal Adenoma and Carcinoma

Colorectal Adenoma and Carcinoma Clinical Trial

Official title: Investigation of the Role of the Microbiome in the Pathogenesis of Colorectal Adenoma and Carcinoma

Status Completed

Clinical Trial Summary

The purpose of this study is the investigation of new host-microbiome interactions promoting adenoma formation and adenocarcinoma progression. For that purpose, the investigators will collect saliva, stool and colon biopsy specimens from patients referred to colonoscopy or surgical resection of colorectal tumor. Besides, a questionnaire about diet, lifestyle and medical history will be collected. Sample analysis will involve simultaneous characterization of host and microbiota genomic and transcriptomic components.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Adenoma
• Carcinoma
• Colorectal Adenoma and Carcinoma

• NCT number: NCT02947607
• Study type: Observational
• Source: Universitaire Ziekenhuizen KU Leuven
• Status: Completed
• Start date: July 2016
• Completion date: April 2019