Clinical Trials Logo
  1. Home
  2. Colonic Polyps
  3. NCT02196649

Clip Placement Following Endoscopic Mucosal Resection - Randomised Trial — CuRB  

Colonic Polyps Clinical Trial

Official title:
Prophylactic and Endoscopic Clip Placement to Prevent Clinically Significant Post Wide Field Endoscopic Mucosal Resection Bleeding - a Randomised Controlled Trial.

Clinical Trial Summary

Patients will be randomised to have endoscopic clips applied to the Endoscopic Mucosal Resection (EMR) site following complete removal of the lesion, or will not receive clips and proceed with standard of care.

Clinical Trial Description

The outlined literature suggests that colonic post EMR bleeding may be prevented by the use of prophylactic endoscopic clips. There has thus far been no prospective study to confirm this concept. The ideal way to prove the hypothesis is to conduct a randomised controlled trial to evaluated the use of prophylactic clip placement on the EMR resection defect, for the purpose of preventing delayed bleeding in colonic wide field EMR (lesions>20mm). Given the significantly increased rate of bleeding in the proximal colon, clip placement in this location may have the greatest benefit. If it is proven that such a prophylactic technique is effective and safe, it may lead to significantly decreased patient morbidity and health care resources associated with the management delayed bleeding. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02196649
Study type Interventional
Source Western Sydney Local Health District
Contact
Status Completed
Phase N/A
Start date October 2014
Completion date March 1, 2021
View Details
See also
  Status Clinical Trial Phase
Completed NCT05615857 - Endocuff Enhanced Colonoscopy: Does it Improve Polyp Detection and Make Rectal Retroflexion Unnecessary N/A
Not yet recruiting NCT02865382 - Detection of Colorectal Adenoma by Optical Enhancement Technology vs. High-Definition Colonoscopy N/A
Completed NCT02529007 - Endo-cuff Assisted Vs. Standard Colonoscopy for Polyp Detection in Bowel Cancer Screening N/A
Completed NCT02245854 - Efficacy and Safety of a New Polypectomy Snare for Cold-polypectomy for Small Colorectal Polyps N/A
Completed NCT01712048 - Submucosal Injection EMR vs. Underwater EMR for Colorectal Polyps N/A
Terminated NCT01297712 - Endoscopic Assessment of Polyp Histology N/A
Active, not recruiting NCT01368289 - Australian Multicentre Colonic Endoscopic Mucosal Resection Study
Not yet recruiting NCT00996619 - Measuring the Spectrum of Tissues During Endoscopy N/A
Completed NCT00997802 - Japanese National Computed Tomographic (CT) Colonography Trial N/A
Completed NCT00468455 - Post-Op Quality of Life After Colorectal Surgery N/A
Completed NCT00018551 - Chemoprevention With Folic Acid Phase 2
Recruiting NCT02552017 - Accuracy of Detection Using ENdocuff Optimisation of Mucosal Abnormalities N/A
Completed NCT01979458 - Photometric Stereo Endoscopy (PSE) as a Tool for Imaging the Rectum and Colon N/A
Unknown status NCT01101672 - Trial for Single Port Versus Conventional Laparoscopic Colectomy Phase 2/Phase 3
Terminated NCT01458925 - Feasibility of Check-Cap's P1 Capsule System Screening N/A
Recruiting NCT05737017 - The Efficacy and Safety of a Hybrid Hemostatic Device (ClearCoajet) N/A
Recruiting NCT02760381 - Acetic Acid for Optical Characterization of Colonic Polyps N/A
Withdrawn NCT04253990 - Efficacy and Safety of Precut-EMR for Resecting of Colonic Polyp N/A
Completed NCT01901510 - Panchromoendoscopy Using Oral Indigo Carmine Mixed With Polyethylene Glycol Prep Phase 1
Completed NCT01761279 - High Definition Endoscopy With i-Scan for Small Colonic Polyp Evaluation: The HiScope Study N/A