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Clip Placement Following Endoscopic Mucosal Resection - Randomised Trial — CuRB  

Colonic Polyps Clinical Trial

Official title:
Prophylactic and Endoscopic Clip Placement to Prevent Clinically Significant Post Wide Field Endoscopic Mucosal Resection Bleeding - a Randomised Controlled Trial.

Clinical Trial Summary

Patients will be randomised to have endoscopic clips applied to the Endoscopic Mucosal Resection (EMR) site following complete removal of the lesion, or will not receive clips and proceed with standard of care.

Clinical Trial Description

The outlined literature suggests that colonic post EMR bleeding may be prevented by the use of prophylactic endoscopic clips. There has thus far been no prospective study to confirm this concept. The ideal way to prove the hypothesis is to conduct a randomised controlled trial to evaluated the use of prophylactic clip placement on the EMR resection defect, for the purpose of preventing delayed bleeding in colonic wide field EMR (lesions>20mm). Given the significantly increased rate of bleeding in the proximal colon, clip placement in this location may have the greatest benefit. If it is proven that such a prophylactic technique is effective and safe, it may lead to significantly decreased patient morbidity and health care resources associated with the management delayed bleeding. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02196649
Study type Interventional
Source Western Sydney Local Health District
Contact
Status Completed
Phase N/A
Start date October 2014
Completion date March 1, 2021
View Details
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