Optical Frequency Domain Imaging for Assessing Colonic Polyps

Status Completed

Clinical Trial Summary

The goal of this research is to conduct a pilot clinical study to image colonic polyps with the intent to evaluate the potential use of Optical Frequency Domain Imaging (OFDI) to identify the extent of invasion (if present), differentiate between hyperplastic polyps and adenomas, and identify serrated polyps.

Clinical Trial Description

The colon OFDI catheter will be used in conjunction with a sigmoidoscope. If a sigmoid polyp is identified, the colonoscope will be removed and a sigmoidoscope inserted. The colon OFDI catheter will be advanced through the sigmoidoscope accessory port and positioned adjacent to the colon wall. Imaging will be performed with the OFDI system across the polyp's surface and the base/stalk if pedunculated. The investigators anticipate that on average the investigators will utilize 4 helical scans per polyp. Each of the scans will take less than 30 seconds. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01439087
Study type	Interventional
Source	Massachusetts General Hospital
Contact
Status	Completed
Phase	N/A
Start date	July 2009
Completion date	August 2010

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT05615857` - Endocuff Enhanced Colonoscopy: Does it Improve Polyp Detection and Make Rectal Retroflexion Unnecessary	N/A
Not yet recruiting	`NCT02865382` - Detection of Colorectal Adenoma by Optical Enhancement Technology vs. High-Definition Colonoscopy	N/A
Completed	`NCT02529007` - Endo-cuff Assisted Vs. Standard Colonoscopy for Polyp Detection in Bowel Cancer Screening	N/A
Completed	`NCT02245854` - Efficacy and Safety of a New Polypectomy Snare for Cold-polypectomy for Small Colorectal Polyps	N/A
Completed	`NCT01712048` - Submucosal Injection EMR vs. Underwater EMR for Colorectal Polyps	N/A
Terminated	`NCT01297712` - Endoscopic Assessment of Polyp Histology	N/A
Active, not recruiting	`NCT01368289` - Australian Multicentre Colonic Endoscopic Mucosal Resection Study
Completed	`NCT02196649` - Clip Placement Following Endoscopic Mucosal Resection - Randomised Trial	N/A
Completed	`NCT00997802` - Japanese National Computed Tomographic (CT) Colonography Trial	N/A
Not yet recruiting	`NCT00996619` - Measuring the Spectrum of Tissues During Endoscopy	N/A
Completed	`NCT00468455` - Post-Op Quality of Life After Colorectal Surgery	N/A
Completed	`NCT00018551` - Chemoprevention With Folic Acid	Phase 2
Recruiting	`NCT02552017` - Accuracy of Detection Using ENdocuff Optimisation of Mucosal Abnormalities	N/A
Completed	`NCT01979458` - Photometric Stereo Endoscopy (PSE) as a Tool for Imaging the Rectum and Colon	N/A
Unknown status	`NCT01101672` - Trial for Single Port Versus Conventional Laparoscopic Colectomy	Phase 2/Phase 3
Terminated	`NCT01458925` - Feasibility of Check-Cap's P1 Capsule System Screening	N/A
Recruiting	`NCT05737017` - The Efficacy and Safety of a Hybrid Hemostatic Device (ClearCoajet)	N/A
Recruiting	`NCT02760381` - Acetic Acid for Optical Characterization of Colonic Polyps	N/A
Withdrawn	`NCT04253990` - Efficacy and Safety of Precut-EMR for Resecting of Colonic Polyp	N/A
Completed	`NCT01901510` - Panchromoendoscopy Using Oral Indigo Carmine Mixed With Polyethylene Glycol Prep	Phase 1