Short- and Long-term Outcomes of Robotic vs Laparoscopic Right Colon Cancer: a 10-year Single-center Retrospective Study

Colon Cancer Clinical Trial

Official title:

the Ethics Committee of the First Affiliated Hospital of Nanchang University

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06454253
• Other study ID #: IIT2023015
• Status: Completed
• Start date: December 1, 2014
• Est. completion date: April 30, 2024

Study information

• Verified date: June 2024
• Source: Nanchang University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The goal of this observational study is to evaluate the short-term outcomes and long-term outcomes of robot-assisted right colon group for cancer compared to laparoscopic-assisted right colon group. This is a large sample study based on ten years of clinical data. The main question it aims to answer is: What are the advantages of da Vinci robot right hemicolectomy compared to laparoscopic right hemicolectomy, and is there a difference in long-term efficacy between the two methods.

Description:

Colorectal cancer (CRC) is highly prevalent worldwide. In China, CRC ranks high among the population of men and women with cancer. The incidence and mortality rates of CRC are rising quickly in developing countries, and it is the fourth most deadly cancer in the world. In particular, the right colon cancer (RCC) is continuously growing in China, and the early symptoms of RCC are not typical. one of the most useful ways for RCC is surgical is a surgical operation. Along with the development of minimally invasive surgery, the use of laparoscopy for colon cancer is widely accepted and has become one symbolic surgical technology. Studies have demonstrated that laparoscopic colonic surgery is related to reduced pain after operation, shorter rehabilitation time, shorter length of hospital stay, reduced the time of ileus after surgery, and reduced surgical site infection.

Nevertheless, laparoscopic surgery also has its shortcoming, including a limited range of motion, slow learning and growth, and physiological tremor cannot be eliminated.The emergence of robots has broken the inherent disadvantage of laparoscopy. It has achieved similar or better results in previous studies. Based on these advantages, robotic surgery has received much attention from the surgeons. With the first robotic surgery in the field of colon cancer was reported in 2002, there are some studies proved the safety and feasibility by using robot,However, most studies with small sample sizes and with cases at a relatively early stage.

Therefore, the purpose of this study is to compare the short-term and long-term outcomes between RARC and LARC in the treatment of right colon cancer in our center.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 1879
• Est. completion date: April 30, 2024
• Est. primary completion date: March 31, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 85 Years

Eligibility

Inclusion Criteria:

1. The age is more than 18 years old and less than or equal to 85 years old

2. No distant metastasis (including pelvic cavity, peritoneum, liver, lung, brain, bone, distant lymph node metastasis, etc.) is judged by ultrasound, CT, PET-CT, etc

3. Preoperative colonoscopy showing that the tumor was located in the ileocecal region, ascending colon, hepatic flexure, or transverse colon with pathology showing malignancy

4. signed informed consent. -

Exclusion Criteria:

1. multiple primary colorectal cancer

2. recurrent right colon cancer

3. preoperative neoadjuvant chemotherapy

4. emergency surgery for intestinal obstruction, bleeding or perforation

5. incomplete data and missing follow-up data. -

Related Conditions & MeSH terms

• Colon Cancer
• Colonic Neoplasms
• Laparoscopic
• Long-term Outcomes

Intervention

Device:
• Da Vinci Robot Surgical System
Performing surgery on right colon cancer patients using the da Vinci robotic surgical system or laparoscopic surgical system

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Taiyuan Li

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	overall survival	months	5 years after surgery
Primary	disease-free survival	months	5 years after surgery
Secondary	the rate of postoperative complications	rate	1 months after surgery
Secondary	operative time	minutes	Intraoperative
Secondary	estimation of blood loss	milliliters	Intraoperative
Secondary	number of retrieved lymph nodes	numbers	Intraoperative
Secondary	days after postoperative hospital stay	days	1 months after surgery
Secondary	time to first exhaust	hours	1 weeks after surgery
Secondary	time to liquid diet	hours	1 weeks after surgery
Secondary	the rate of intracorporeal anastomosis	rate	1 months after surgery