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NCT05388513 Clinical Trial

Evaluating Factors Affecting Survival in Colon and Rectum Cancer

Colon Cancer Clinical Trial

Official title:
Evaluating Factors Affecting Survival in Colon and Rectum Cancer: A Prospective Cohort Study With 161 Patients

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05388513
Other study ID # ColoRectalCancers
Secondary ID
Status Completed
Phase
First received
Last updated
Start date January 2009
Est. completion date January 2014

Study information
Verified date May 2022
Source Umraniye Education and Research Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Colorectal cancers are frequent among cancers of the gastrointestinal system. Whether there are any differences between survival in rectum and colon cancer patients is controversial. This study aimed to compare survival in the surgically treated rectum and colon cancers and determine the factors affecting survival.

Description:

Colorectal cancers are frequent in the gastrointestinal system. It is the 4th most common cancer after lung, prostate, and bladder in the male population and it is the 3rd after breast and thyroid cancers in the female population according to World Health Organization. It is considered significant morbidity and mortality cause and is estimated to develop in more than 1.000.000 individuals annually worldwide. Colorectal cancers form 10% of all cancers in the female and male populations. It is the 2nd most common cause of death among cancers in the United States of America. In studies, it is stated that the risk of developing colorectal cancer in an individual is 5-6%. Also, the risk of death of an individual due to colorectal cancer was determined as 3%. In the last 50 years, the rate of colorectal cancer mortality decreased in the female population while it did not change in the male population. Whether there is a difference in survival time between rectum and colon cancers is controversial. With the development in neoadjuvant treatment approaches, poor prognosis in past years got better. Recent studies show that the prognosis in rectum cancers is better than in colon. Nevertheless, factors affecting prognosis other than treatment for both colon and rectum cancers are not clarified. In this study, the investigators aimed to evaluate the surgically treated rectum and colon cancer patients' survival and factors affecting survival time.

Recruitment information / eligibility
Status Completed
Enrollment 161
Est. completion date January 2014
Est. primary completion date December 2013
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: Patients who were operated and diagnosed histopathologically as adenocarcinoma were included. Exclusion Criteria: Inoperable and recurrent colorectal cancer patients and patients that were diagnosed with other than adenocarcinoma were excluded from the study.

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Surgical Resection
Surgically treated patients included

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Umraniye Education and Research Hospital

Outcome
Type Measure Description Time frame Safety issue
Primary Survival 5 year survival data is used. 5 year
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