Usefulness of Chromoendoscopy in Diagnosing Microscopic Colitis

Collagenous Colitis Clinical Trial

Official title: Prospective Study on the Usefulness of Chromoendoscopy in Detecting Microscopic Colitis in Patients Undergoing Colonoscopy Due to Chronic Watery Diarrhoea

Status Recruiting

Clinical Trial Summary

The purpose of this study is to determine whether chromoendoscopy using Indigo-Carmine dye spray is useful in diagnosing microscopic colitis among patients undergoing colonoscopy due to chronic watery diarrhea.

Clinical Trial Description

Microscopic colitis is a common disease found in 10% to 20% of cases having chronic watery diarrhea. Obvious endoscopically identifiable changes of the mucosal surface are usually absent, thus diagnosing microscopic colitis relies on multiple biopsy sampling from all segments of the colon. Chromoendoscopy using indigo-carmine dye spray might, however, unravel mucosal changes in microscopic colitis (Suzuki 2011).

The aim of this study is to investigate if chromoendoscopy using Indigo-Carmine 0.2-0.5% in patients with chronic watery diarrhea is useful in diagnosing microscopic colitis. ;

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

• Chronic Diarrhoea
• Colitis
• Colitis, Microscopic
• Collagenous Colitis
• Diarrhea
• Lymphocytic Colitis

• NCT number: NCT01504048
• Study type: Interventional
• Source: Karolinska University Hospital
• Contact: Peter T Schmidt, MD, PhD
• Phone: +46 8 51770000
• Email: peter.thelin.schmidt@ki.se
• Status: Recruiting
• Phase: N/A
• Start date: June 2009
• Completion date: December 2016