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Colitis clinical trials

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NCT ID: NCT02289417 Completed - Ulcerative Colitis Clinical Trials

Efficacy and Safety Study of Apremilast to Treat Active Ulcerative Colitis

UC
Start date: January 8, 2015
Phase: Phase 2
Study type: Interventional

The purpose of the study is to evaluate the clinical efficacy, safety and tolerability of apremilast (30 mg twice daily [BID] and 40 mg BID), compared with placebo, in participants with active Ulcerative Colitis (UC).

NCT ID: NCT02280629 Completed - Ulcerative Colitis Clinical Trials

Phosphatidylcholine (LT-02) vs. Placebo vs. Mesalamine for Maintenance of Remission in Ulcerative Colitis (PROTECT-2)

PROTECT-2
Start date: October 1, 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study is to prove the superiority of a 48-weeks treatment with 3.2 g/day delayed-release phosphatidylcholine (LT-02) versus placebo for the maintenance of remission in patients with ulcerative colitis (UC)

NCT ID: NCT02274714 Completed - Ulcerative Colitis Clinical Trials

Dysmenorrhea in Women With Crohn's Disease and Ulcerative Colitis

Start date: May 2010
Phase: N/A
Study type: Observational

This case-control study will screen for dysmenorrhea and assess severity of menstrual symptoms in menstruating women with CD and UC compared with healthy age-matched controls. IBD activity will be characterized using previously validated clinical disease activity indices. General and health-related quality of life will be assessed using validated measures.

NCT ID: NCT02267694 Completed - Ulcerative Colitis Clinical Trials

Study of Freeze-dried Black Raspberry in Maintenance of Ulcerative Colitis

BRB
Start date: August 2013
Phase: Phase 1
Study type: Interventional

This research study is about adding Black Raspberry powder to the treatment regimen of patients with ulcerative colitis who are currently in remission and doing well.

NCT ID: NCT02265588 Completed - Depression Clinical Trials

Healthy Approach to Physical and Psychological Problems in Youngsters With IBD (HAPPY-IBD).

HAPPY-IBD
Start date: September 2014
Phase: N/A
Study type: Interventional

The presented study aims to reduce symptoms of depression and anxiety in adolescents with inflammatory bowel disease and increased symptoms of anxiety and depression by using the disease specific CBT program (PASCET-PI)in order to improve quality of life and to improve the clinical course of disease.

NCT ID: NCT02261636 Completed - Ulcerative Colitis Clinical Trials

Induction and Maintenance of Remission With Pentasa as Ulcerative Colitis Treatment

IMPACT
Start date: January 2015
Phase:
Study type: Observational

For both induction of remission and in maintenance of remission, different doses and treatment durations are used in practice. The aim of this study is to assess how mesalazine is used in clinical practice, at which doses and for how long and how these differences impact the patient disease state and work productivity.

NCT ID: NCT02229344 Completed - Colitis, Ulcerative Clinical Trials

Study of Clinical Course of Newly Diagnosed Moderate to Severe Ulcerative Colitis in Korea

MOSAIK
Start date: July 1, 2014
Phase:
Study type: Observational

The purpose of this study is to describe clinical course of newly diagnosed moderate to severe ulcerative colitis (chronic inflammatory disease of the colon) in tertiary referral hospitals in Korea for 5-year follow-up under usual care.

NCT ID: NCT02227342 Completed - Ulcerative Colitis Clinical Trials

Fecal Microbiota Transplantation (FMT) in the Management of Active Ulcerative Colitis

Start date: July 2014
Phase: Phase 1/Phase 2
Study type: Interventional

Manipulation of the intestinal microbiota through FMT is a potential therapeutic target for IBD patients. Studies are now required to determine if repeated FMT can overcome the apparent immune response to FMT thereby maintaining sustained clinical improvement and remission. Prior to a large randomized controlled trial of FMT in UC we will carry out a feasibility study to determine if serial FMTs can sustain a clinical response and maintain stability of transplanted microbiota.

NCT ID: NCT02213835 Completed - Ulcerative Colitis Clinical Trials

Treatment With the Specific Carbohydrate Diet for Children With Active Crohns Disease and Ulcerative Colitis

SCD
Start date: June 2014
Phase: N/A
Study type: Interventional

The aim of this study is to determine the tolerability and potential efficacy of dietary therapy, the Specific Carbohydrate Diet (SCD), in pediatric patients with Crohn's disease (CD) and Ulcerative Colitis (UC). This is a single center, open labelled study designed to determine tolerability, preliminary safety and potential efficacy in pediatric patients with CD and UC. The study patients will be recruited from Seattle Children's GI clinic. the investigators will enroll 10 patients with mild to moderate CD (defined as PCDAI score of 10-29) or Ulcerative colitis (PUCAI 10-60) ages 8 to 21 years. Each patient will be in the study for approximately 12 weeks.

NCT ID: NCT02200445 Completed - Ulcerative Colitis Clinical Trials

Low Dose IL-2 for Ulcerative Colitis

Start date: February 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the safety and maximum effective dose (MED) of Interleukin-2 in subjects with moderate-to-severe ulcerative colitis.