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COLD clinical trials

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NCT ID: NCT06158659 Recruiting - Flu Clinical Trials

Improved Immunology Outcomes Associated With Lactoferrin Fortified With HMO in Infant Formula

Start date: November 14, 2023
Phase: N/A
Study type: Interventional

The goal of this interventional clinical trial is to test the effectiveness of enhancing immunity in newly born infants fed with Feihe investigational formula product containing Lactoferrin fortified with HMO. The main question it aims to answer is: - whether the immunity functions of participants in terms of frequency of catching flu and cold in the study product arm is significantly better than participants assigned in the other two arms. 240 qualified participants will be randomized to 3 arms (investigational formula, control formula, and breast-feeding) to consume assigned formula or breast-feeding for 12 months according to protocol. There will be up to 6 site visits arranged for each participant during the study, and all relevant clinical and questionnaire data, including the most important primary outcome - frequency of catching flu and cold for each visit interval, will be captured, recorded and entered to CMTS (Clinical Management Trial System) for statistical analysis and reporting. Researchers will compare the three arms to validate the assumption that the consumption of Feihe investigational formula product containing Lactoferrin fortified with HMO will improve immunity in newly born infants, along with physical development.

NCT ID: NCT05728918 Recruiting - Clinical trials for Fatigue Syndrome, Chronic

Effectiveness of Antrodia Cinnamomea Mycelia on Improving Immune Response in Subhealth People

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

This study aims to assess the effect of Antrodia cinnamomea mycelia on immune modulation in subhealth people.

NCT ID: NCT05454826 Recruiting - Migraine Clinical Trials

Investigation of the Effect of Cold Application in Migraine

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

Migraine is a headache that is paroxysmal and can last for hours, sometimes even days due to untreated or ineffective treatment is usually unilateral, throbbing, severe enough to prevent the person's daily life activities, and increases with head movements. It is a chronic disorder characterized by recurrent moderate and severe headaches, mostly associated with a few symptoms in the autonomic nervous system. Migraine consists of recurrent headache attacks accompanied by neurological, gastrointestinal, and autonomic symptoms. Migraine is the most common chronic headache in epidemiological studies. Studies have shown that migraine affects 12% of the general population. The aim of migraine treatment is to reduce the frequency, duration, and severity of migraine attacks, to reduce the losses caused by migraine, and increase the quality of life. In the treatment of migraine, non-pharmacological treatment is as important as pharmacological treatment. Some individuals prefer drug-free treatment methods because of the side effects drugs. In recent years, as the mechanisms of headaches have been better understood, significant developments have been made in treatment methods. Different physiotherapy and rehabilitation methods have been used for treatment. There are studies in which cold application is used in migraine patients, but a study evaluating the effectiveness of cold application has not been found in the literature. The systemic effects of cold have two main purposes: to maintain the current body temperature and to produce energy to raise the fallen body temperature. Knowing both the local and systemic effects of cold guides its use in treatment. The aim of this study was to diagnose migraine. To investigate the effectiveness of cold application applied in addition to relaxation exercises in individuals.

NCT ID: NCT05435144 Recruiting - COVID-19 Clinical Trials

Elderberry for Immune Support

Start date: August 26, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to confirm and quantify the effects of ElderCraft® elderberry extract on immune health.

NCT ID: NCT04277494 Recruiting - Athletic Injuries Clinical Trials

The Acute Effect of Cold Spray Application on the Mechanical Properties of the Quadriceps Muscle in Athletes

Start date: January 12, 2020
Phase: N/A
Study type: Interventional

Vikocoolant spray, also known as cold spray; It is a form of cryotherapy (cold treatment) used in sports medicine, athletic training, sports competitions and rehabilitation environments. It has been demonstrated in the literature that local cold application may cause increased resistance to movement. It has been reported in some studies that muscle can change its mechanical properties in a short time. However, the effect of cold spray application on the mechanical properties of the muscle is unknown. Therefore, in the current study proposal, the investigators aim to investigate the acute effect of cold spray application on the mechanical properties of the quadriceps muscle in athletes.

NCT ID: NCT02457533 Recruiting - COLD Clinical Trials

Case Management - Active Telephone Support to Patients With COLD

Start date: April 2015
Phase: N/A
Study type: Interventional

To investigate the effects of patient counseling by telephone on Quality of Life and the use of Health care system.

NCT ID: NCT02183779 Recruiting - Cold Clinical Trials

PORH and Response to Cold in Raynaud's Phenomenon.

REFRAIN
Start date: June 2014
Phase: N/A
Study type: Interventional

The main objective of the study is to determine if implication of epoxy-eicosatriénoïc acids (EETs) and NO during cutaneous post-occlusive hyperemia differs between patients with Raynaud phenomena and healthy volunteers, by studying hyperaemic postocclusive response after microinjection of fluconazole and L-NMMA at the dorsal side of the fingers.