Cognitive Impairment Clinical Trial
Official title:
Functional Magnetic Resonance Imaging Study to Explore the Mechanism and the Efficacy and Safety of Jianpi Yishen Huatan Granule for Cognitive Impairment After Acute Cerebral Infarction
The purpose of this study is to explore the pathogenesis of cognitive impairment after acute cerebral infarction by applying the multimodal function MRI to dynamically observe the changes of the value of NAA,Cho,Cr,FA in a certain region in the brain and the function of the brain ,and to provide a visual instrument for evaluating the therapeutical effects of Chinese medicine through the application of multimodal function MRI to observe the changes of the neurotransmitter in certain area in the brain before and after the treatment.
The present study is designed to assess the efficacy and safety of Jianpi Yishen Huatan
granules with cognitive impairment after Acute Cerebral Infarction by fMRI and
neuropsychology scales,as well as observe the symptoms,syndrome characteristics and
neuropsychological changes of patients with cognitive dysfunction after acute cerebral
infarction.And explore the pathogenesis of cognitive impairment after acute cerebral
infarction by applying the multimodal function MRI to dynamically observe the changes of the
value of NAA,Cho,Cr,FA in a certain region in the brain and the function of the brain ,and to
provide a visual instrument for evaluating the therapeutical effects of Chinese medicine
through the application of multimodal function MRI to observe the changes of the
neurotransmitter in certain area in the brain before and after the treatment.
The sample size is 40 of which 20 are from the intervention group and 20 are from the control
group.
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