Acute Health Effects of Low Temperature Exposure

Status Not yet recruiting

Clinical Trial Summary

This is a randomized controlled human exposure crossover study. Investigators aims to assess the acute effects of low temperature exposure and the underlying mechanisms.

Clinical Trial Description

The investigators will conduct a randomized controlled human exposure crossover study among about 50 healthy young adults in Shanghai, China. Each subject will be exposed twice: once to the low temperature (16#) and once to the moderate temperature (22#) in a chamber for about 2-2.5 hours. During the exposure session, each subject will be requested to rest. Health examinations will be conducted immediately prior to exposure (within 1 hour before the exposure session), during the period of exposure, and after exposure (within 2 hours after the exposure session). Health examinations include spirometry, Holter monitoring, blood pressure tests, cognitive function tests, symptom questionnaires, and magnetic resonance imaging. Investigators plan to collect blood, urine, exhaled breath condensate, and oropharyngeal swabs samples. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06076629
Study type	Interventional
Source	Fudan University
Contact	Haidong Kan, PhD
Phone	+86-021-54237908
Email	kanh@fudan.edu.cn
Status	Not yet recruiting
Phase	N/A
Start date	October 10, 2023
Completion date	December 31, 2024

View Details

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