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Effect of Acetaminophen Preemptive Analgesia on Postoperative Cognitive Function

Cognitive Function Clinical Trial

Official title:
Effects of Acetaminophen Preemptive Analgesia on Anesthesia Recovery Time and Postoperative Cognitive Function in Patients Undergoing Gastrointestinal Tumor Surgery

Clinical Trial Summary

Patients undergoing gastrointestinal tumor surgery are prone to delayed recovery and postoperative cognitive dysfunction due to greater trauma and longer operation time. Pre-analgesia can reverse the effects of nociceptive stimulation on recovery from general anesthesia and postoperative cognitive function. Intravenous injection of non-steroidal drugs can effectively reduce postoperative pain and the use of opioids. Therefore, This study selected acetaminophen mannitol injection for preemptive analgesia to observe the effects on anesthesia recovery time and postoperative cognitive function of patients undergoing gastrointestinal tumor surgery, providing new ideas for reducing cognitive dysfunction in patients undergoing gastrointestinal tumor surgery

Clinical Trial Description

By administering acetaminophen to patients with gastrointestinal tumors before surgery, recording the time to recovery from anesthesia, and assessing cognitive function status by CAM on the first, third, and seventh day after surgery ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06004687
Study type Interventional
Source Affiliated Hospital of Nantong University
Contact Hongsheng Chen
Phone +86 513 81160313
Email chenhongsheng8@163.com
Status Recruiting
Phase Phase 1/Phase 2
Start date July 26, 2023
Completion date December 30, 2024
View Details
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