Clinical Trial Details
— Status: Not yet recruiting
Administrative data
| NCT number |
NCT05152719 |
| Other study ID # |
119418 |
| Secondary ID |
|
| Status |
Not yet recruiting |
| Phase |
N/A
|
| First received |
|
| Last updated |
|
| Start date |
December 2, 2021 |
| Est. completion date |
June 30, 2022 |
Study information
| Verified date |
June 2021 |
| Source |
Western University, Canada |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Interventional
|
Clinical Trial Summary
Several lifestyle modifications, such as manipulating diet and exercise, have been shown to
enhance cognitive function. This study aims to determine if a combination of Sprint Interval
Training (SIT) and Time Restricted Eating (TRE) elicits greater enhancements in cognitive
function than either of these interventions alone. SIT and TRE have both been proven to have
high adherence rates and require minimal lifestyle changes, therefore the implementation of
these may allow for a feasible method of improving cognition in healthy populations. A group
of young adults will be randomized into either a SIT group, TRE group, or a SIT+TRE group. To
assess the changes in cognitive function, cognitive tests will be performed at baseline and
biweekly. Secondly, we will be monitoring the differences in the three groups in terms of
body composition, which will be measured using a BodPod. It is hypothesized that the SIT+TRE
group will display the greatest improvements in cognitive function and body composition
versus the TRE only group and the SIT only group.
Description:
This study will explore how a combination of a time restricted eating (TRE) strategy and a
sprint interval training (SIT) exercise program will affect cognitive function. Both TRE and
SIT have been shown to present significant brain challenges, and are both easily implemented
lifestyle habits. Participants will be randomized into 3 groups of either SIT alone, TRE
alone, or SIT + TRE. We will be assessing acute effects (single day of TRE, followed by a
single session of SIT the next day), and the effects over a 6 week period. The SIT protocol
consists of four 30 second sprinting bouts, separated by 2 minutes of recovery. An additional
sprint bout will be added biweekly to maintain progressive overload. SIT will be performed 3
times a week for the treatment group. The TRE involves no restrictions on the type or amount
of food consumed, however, food must be consumed between 12pm and 8pm. The SIT will occur in
an unfed state towards the end of the fast. The study will involve sedentary young adults. To
evaluate the success of the intervention, 2 cognitive tests (Stroop and Corsi block) will be
performed at baseline and biweekly over a 6 week treatment period. Additionally, body
composition testing will occur at baseline and once every three weeks using a BodPod. We
hypothesize that the combination treatment group will have greater improvements in their
cognitive function and body composition compared to either intervention alone.
