Pain Effect on Attention Using an Ipad Game App

Status Recruiting

Clinical Trial Summary

Cognitive performance will be studied over time using an iPad game interface called the nine choice human game (5CH) in normal volunteer subjects before during and after experimentally induced thermal (cold or warm) pain or control (no intervention).

Clinical Trial Description

Purpose: to assess the effects of pain on performance in a computer game interface of attention and memory and reliability of the repeated testing. Rationale: The perioperative period may alter the ability to play an iPad game through changes in attention or memory as result of surgery, anesthesia, pain or medications. This study will describe and quantify and isolate any short term reduction in ability to focus and pay attention to the presence of thermal (cold or warm) pain. Objectives: Determine if cognitive function is altered from thermal pain (cold or warm) using simple computer/ipad games of attentional performance and cognitive function. Design and Outcomes: In group 1: no interventions will be used and the subjects will play the ipad game at baseline, 5 minutes later and 10 minutes later. In group 2: The subjects will play the ipad game, then 5 minutes later a thermal probe at 47 degrees C for 90 seconds on the arm or leg will be used while the game is being played. Following 10 minutes of recovery, the subject will play the game again, 5 minutes later the subject will have the foot placed in 10 degree water bath or body temperature water bath while the game is played, and the game will be played 10 minutes later after the foot is warm and dry. Visual analog scale (VAS) pain score from 0-10 will be used to assess discomfort. The subject will be able to stop the game or withdraw at any point. The primary outcome measures will be median cue duration (MCD) in the 9CH game. Secondary outcome measures will be number of correct, incorrect, omissions, time to finish trials, and time to quit for the 9CH. A total of 60 subjects will be studied, 20 subject warm probe/cold water, 20 subjects warm probe/body temperature water, and 20 normal subjects with no intervention. ;

Study Design

Related Conditions & MeSH terms

Cognitive Function

Clinical Trial Details

NCT number	NCT03115788
Study type	Interventional
Source	Wake Forest University Health Sciences
Contact	Douglas Ririe, MD, PhD
Phone	(336) 716-7179
Email	dririe@wakehealth.edu
Status	Recruiting
Phase	N/A
Start date	May 15, 2016
Completion date	December 2024

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05563805` - Exploring Virtual Reality Adventure Training Exergaming	N/A
Completed	`NCT03708692` - Menstrual Cycle Phases on Recovery and Cognitive Function
Active, not recruiting	`NCT04505345` - Virtual Reality Cognitive Training in Alcohol Use Disorder	N/A
Completed	`NCT04430465` - Effects of Wholegrains on Children's Health (KORN)	N/A
Completed	`NCT02915913` - Effects of Exercise Training on Cognitive Function and Neurotrophic Factors in Overweight Adults	N/A
Completed	`NCT01410097` - Physical and Cognitive Function - Look AHEAD Ancillary Study	N/A
Completed	`NCT03826121` - Efficacy and Safety of Sesame Oil Cake Extract on Improvement of Cognitive Function	N/A
Recruiting	`NCT05621278` - Children to Adults Mental and Psychosomatic Health Study (CAMPS)
Completed	`NCT05498415` - Feasibility, Acceptability, and Efficacy of the Sleep Move Stand Study	N/A
Completed	`NCT03208569` - Anticholinergic Burden - Treatment Optimization
Completed	`NCT03793777` - The Effect of Aronia Melanocarpa Extract on Cognitive Function	N/A
Recruiting	`NCT05525299` - Reminiscence-Based Life Review on Copying With Existential Suffering Among Older Cancer Survivors	N/A
Completed	`NCT03698123` - Performance Nutrition for Residents and Fellows	N/A
Completed	`NCT04543500` - Self-regulation of Prefrontal Cortex During Emotional Cognitive Control	N/A
Recruiting	`NCT05891977` - Effect of Tomato Paste Consumption on the Microbiota-gut-brain Axis in Healthy Adults	N/A
Recruiting	`NCT05591885` - Nutrilite Memory Builder on the Improvement of Cognitive Function	N/A
Active, not recruiting	`NCT05575752` - Acute Health Effects of High Temperature Exposure	N/A
Completed	`NCT03716609` - Effects of Magnesium Supplementation on Hemodynamic Parameters and Cognitive Function	N/A
Completed	`NCT02763514` - The Effects of DHA- and EPA-enriched Oils on Cognitive Function and Mood	N/A
Completed	`NCT02675621` - Investigation of Acute Mood and Cognitive Performance Effects of Beverages Containing Phenolics in Healthy Adults	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.