Cognitive Dysfunction Clinical Trial
Official title:
Long-term Consequences of Neuroimaging and Perceived Cognitive Dysfunction in Obstetrics Posterior Reversible Encephalopathy Syndrome
NCT number | NCT05140850 |
Other study ID # | 82001568 |
Secondary ID | |
Status | Not yet recruiting |
Phase | |
First received | |
Last updated | |
Start date | January 2022 |
Est. completion date | October 2023 |
The purpose of this study is to explore the long-term consequences of neuroimaging and perceived cognitive dysfunction in obstetrics posterior reversible encephalopathy syndrome.
Status | Not yet recruiting |
Enrollment | 500 |
Est. completion date | October 2023 |
Est. primary completion date | October 2023 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 15 Years to 60 Years |
Eligibility | Inclusion Criteria: 1. patients were diagnosed of PE or E 2. patients received cranial image examination 3. patients consent to participate Exclusion Criteria: 1. patients combined other neurological diseases 2. patients combined mental illness |
Country | Name | City | State |
---|---|---|---|
China | Department of Obstetrics and Gynecology, Key Laboratory for Major Obstetric Diseases of Guangdong Province, The Third Affiliated Hospital of Guangzhou Medical University | Guangzhou |
Lead Sponsor | Collaborator |
---|---|
Dunjin Chen |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | neuroimaging examination | the degree of white matter lesions(0,normal; 1, limited cortical or subcortical white matter oedema; 2, white matter oedema > cortical oedema, white matter oedema extending into deep white matter; 3, white matter oedema > cortex oedema, oedema extending to the ventricular surface; 4, the involved regions substantially extend to the ventricular surface and are almost completely con?uent; 5, involved regions are fully con?uent and continuous, ventricular deformity due to the oedema).The value of fractional anisotropy(FA) in PRES group may higher than non- PRES group, and mean diffusivity (MD) in PRES group may lower than non- PRES group. | within 10 years after deliver | |
Primary | neuro-cognitive test of Mini-mental State Examination | the scores of Mini-mental State Examination,normal (27-30);mild (21-26); moderate (10-20); severe (0-9). | within 10 years after deliver | |
Primary | neuro-cognitive test of Montreal Cognitive Assessment | the scores of Montreal Cognitive Assessment,normal (=26); abnormal (<26). | within 10 years after deliver | |
Primary | blood pressure and hypertension | Hypertension: blood pressure =140/90 mmHg | within 10 years after deliver | |
Primary | level of lactate dehydrogenase(LDH) | inflammatory: LDH>380U/L | within 10 years after deliver | |
Primary | level of LDL in blood | hyperlipidemia:LDL>3.12mmol/L | within 10 years after deliver |
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05273125 -
MOBility Disorders Assessment in Patients With Mild COGnitive Disorders
|
||
Active, not recruiting |
NCT04049695 -
Improving Cognition After Cancer
|
N/A | |
Completed |
NCT05912374 -
Adapting a Behavioral Intervention to Accommodate Cognitive Dysfunction in People Who Inject Drugs
|
N/A | |
Recruiting |
NCT03977350 -
Association Between qEEG Measure and Post-Operative Cognitive Dysfunction (POCD) and Postoperative Delirium (POD)
|
||
Not yet recruiting |
NCT06027632 -
Remotely Supervised Computerized Cognitive Stimulation to Reduce Post-chemotherapy Cognitive Difficulties in Patients Treated for Localized Breast Cancer
|
N/A | |
Terminated |
NCT00754052 -
Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 11 To 17
|
Phase 3 | |
Terminated |
NCT00754013 -
Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 6 To 10
|
Phase 3 | |
Completed |
NCT00719628 -
Depth of Anaesthesia and Cognitive Dysfunction
|
N/A | |
Recruiting |
NCT05014399 -
Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy
|
||
Completed |
NCT04966455 -
Effect of Raisins on Cognitive Function in Healthy Older Adults
|
Phase 3 | |
Recruiting |
NCT05372159 -
Vanderbilt Memory and Aging Project
|
||
Completed |
NCT03243279 -
BRS and Outcomes in Cardiothoracic Surgery
|
||
Completed |
NCT04093882 -
The Relevance of the Blood-brain Barrier to Cognitive Dysfunction and Alzheimer's Disease
|
||
Recruiting |
NCT05732285 -
A Pilot Randomized Controlled Trial: CoINTEGRATE
|
N/A | |
Completed |
NCT06059768 -
Urdu Translation and Psychometric Analysis of Lawton IADLS.
|
||
Completed |
NCT04624529 -
Validity and Reliability of a Self-evaluation Tool for Cognitive Deficits in the Acute Stage After Stroke
|
||
Completed |
NCT04562662 -
Evaluation of mediVR-KAGURA Guided Therapy
|
N/A | |
Not yet recruiting |
NCT04079075 -
Multiple Interventions to Prevent Cognitive Decline
|
N/A | |
Active, not recruiting |
NCT04638101 -
Building the Path to Resilience in Preterm Infants: Mindfulness-based Intervention
|
N/A | |
Active, not recruiting |
NCT04556305 -
Lifestyle Physical Activity and Cognitive Training Interventions
|
N/A |