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Aronia and Cognitive Fitness

Cognition Clinical Trial

Official title:
Aronia and Cognitive Fitness: Focus on Brain Insulin-Sensitivity and Vascular Function

Clinical Trial Summary

Previously, beneficial effects of Aronia Melanocarpa extract (AME) supplementation on cognitive performance has been observed in healthy middle-aged adults. However, underlying mechanisms have not yet been addressed. In addition, effects of AME are unknown in subjects at increased risk of cognitive impairment. It is hypothesized that supplementation with AME enhances (regional) brain vascular function and brain insulin-sensitivity, thereby improving cognitive function of subjects at increased risk of cognitive impairment. The primary objectives are to investigate effects of AME intake on brain vascular function and insulin-sensitivity in cognitive-control brain areas, while we will also evaluate changes in cognitive function (secondary objective). The present study is a randomized, double-blind, placebo-controlled, cross-over trial consisting of two study groups and a pre- and post-test day in both study arms.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05268133
Study type Interventional
Source Maastricht University Medical Center
Contact
Status Active, not recruiting
Phase N/A
Start date June 8, 2022
Completion date August 2023
View Details
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