Thromboelastometry in Liver Transplantation

Status Recruiting

Clinical Trial Summary

Thromboelastometry better assess coagulation than standard coagulation test in patients undergoing ortothopic liver transplantation. In a post-hoc analysis from a randomized study recently conducted by our group, presurgical values of MA10 Extem < 35 mm are highly predictive of RBC administration , with no further improvement over MA10 Extem >40 mm ; suggesting that MA10 Extem between 35-40 would be the optimal range to manage blood product administration. The aim of the study is to validate this result in a prospective cohort of patients submitted to ortothopic liver transplantation.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03011827
Study type	Interventional
Source	Hospital Clinic of Barcelona
Contact	Annabel Blasi, MD, PhD
Phone	+34679500857
Email	ablasi@clinic.ub.es
Status	Recruiting
Phase	N/A
Start date	August 1, 2019
Completion date	October 2022

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT01912547` - Thromboelastography During Surgery for Malignant Pleural Mesothelioma	Phase 0
Completed	`NCT03674684` - ROTEM Assessment of Modern Crystalloid, Hydroxyethyl Starch and Gelatin Effect on Coagulation
Recruiting	`NCT05874843` - Validation of Point-of-care Thromboelastography (TEG 6s) in Pediatric Patients	N/A
Withdrawn	`NCT04705701` - Comparing Post Cardiac Surgery Outcomes in ESRD Patient's With Early Dialysis Versus Standard Care	N/A
Not yet recruiting	`NCT04515420` - The Influence of Noradrenaline on Coagulation and Fibrinolysis in Severe Isolated Brain Injury
Completed	`NCT01598831` - Phase 3 Safety and Efficacy Study of ART-123 in Subjects With Severe Sepsis and Coagulopathy	Phase 3
Completed	`NCT04580563` - Study Assessing Efficacy of Plasmatherapy in Septic Shock-induced Coagulopathy: Feasibility Study	N/A
Withdrawn	`NCT04274699` - Clinical Evaluation of the Hemosonics Quantra® Coagulation Monitor in Liver and Multivisceral Transplantation
Terminated	`NCT02540434` - Trial of RiaSTAP Versus Cryoprecipitate to Lower Operative Transfusions	N/A
Completed	`NCT02203968` - Fibrinogen in the Initial Resuscitation of Severe Trauma (FiiRST)	Phase 1/Phase 2
Unknown status	`NCT01854476` - Safety and Efficacy Study Comparing Pad-gauze With Anti-fibrinolytic Agent Hemostopan™) to a Regular Pad-gauze	Phase 2/Phase 3
Completed	`NCT00816127` - Prevention of Bleeding in Patient With Cirrhosis Undergoing Dental Extraction	N/A
Active, not recruiting	`NCT02926274` - Transfusion Using Stored Whole Blood	N/A
Completed	`NCT05295693` - Quantra vs TEG for Congenital Cardiac Surgery - a Pilot Validation Study
Not yet recruiting	`NCT04582188` - The Early Coagulopathy for the Prognosis in Sepsis
Recruiting	`NCT04528888` - Steroids and Unfractionated Heparin in Critically Ill Patients With Pneumonia From COVID-19 Infection	Phase 3
Recruiting	`NCT05449834` - Fibrinogen Early In Severe Trauma StudY II	Phase 3
Withdrawn	`NCT04435015` - The Utility of Camostat Mesylate in Patients With COVID-19 Associated Coagulopathy (CAC) and Cardiovascular Complications	Phase 1/Phase 2
Not yet recruiting	`NCT04115722` - Coagulation Parameters in IBD Patients
Completed	`NCT01228058` - A Prospective Evaluation of Thromboelastography for Identifying Coagulopathy in Severely Injured Patients	N/A