Clinical Trials Logo

Clinical Trial Summary

The Perosphere Technologies' PoC Coagulometer measures clotting times of fresh whole blood samples. Clotting is initiated by glass surface activation and terminates on optical detection of fibrin assembly, the final step in the coagulation cascade. Since activation occurs at the top of the intrinsic pathway and detection occurs at the bottom of the final common pathway, the Perosphere Technologies' PoC Coagulometer has shown sensitivity to a broad range of drugs and reagents that affect blood clotting processes, including the Direct Oral Anticoagulants, DOACs (e.g. rivaroxaban, apixaban, and edoxaban), as well as the heparins (e.g. enoxaparin, a low molecular weight heparin, and unfractionated heparin). The purpose of the present study is to characterize the performance of the PoC Coagulometer measuring Clotting Time Controls, as well as fresh whole blood from both healthy volunteers and DOAC patients at three field testing sites.

Clinical Trial Description


Study Design

Related Conditions & MeSH terms

NCT number NCT04868214
Study type Observational
Source Sciema UG
Contact Andreas Pfuetzner, Prof.
Phone +4961315884640
Email [email protected]
Status Recruiting
Start date April 20, 2021
Completion date September 30, 2021

See also
  Status Clinical Trial Phase
Completed NCT03255187 - Effect of Dietary Supplemental Fish Oil in Alleviating Health Hazards Associated With Air Pollution N/A
Completed NCT02239744 - Intervention Study on the Health Impact of Air Filters in Chinese Adults N/A
Completed NCT00143715 - Oral Vitamin K for Warfarin Associated Coagulopathy Phase 3
Completed NCT00794755 - Low Dose Supplementation to Improve Anticoagulation Control With Oral Vitamin K as an Adjuvant to Warfarin Therapy Phase 3
Recruiting NCT04377490 - Thrombo Embolic Events in Hospitalized Patients With Covid-19 Serious Acute Pneumopathy
Withdrawn NCT01121510 - Hemostatic Closure of Femoral Artery Access Site, Using the QuickClose Design 9 System Phase 1/Phase 2
Completed NCT03820401 - Dialysis Performance of Different Dialyzer Membranes Using Different Coagulation Strategies N/A
Not yet recruiting NCT04299828 - Evaluation of Pro-Inflammatory Leukocyte Activity in Patients Undergoing Cardiac Surgery
Not yet recruiting NCT04744688 - Changes in Coagulation in Colorectal Cancer Patients Undergoing Surgical Treatment
Not yet recruiting NCT04746391 - Impact of Clotting on Dialyzer Efficiency N/A
Terminated NCT00909298 - Left Ventricular Assist Device (LVAD) Specialized Centers of Clinically Orientated Research (SCCOR) Coagulation - Acute Intrinsic Pathway Antagonist (IPA) Phase 2
Completed NCT02339415 - Targeted Anticoagulation Therapy to Reduce Inflammation and Cellular Activation in Long-term HIV Disease Phase 2
Terminated NCT01428102 - RapidTEG MA Validation N/A
Completed NCT00990158 - Does Low Dose Oral Vitamin K Improve International Normalized Ratio (INR) Stability? Phase 3
Completed NCT00705991 - Validation of Thrombelastometry (ROTEM®) Phase 4
Completed NCT03418363 - How DHEA Supplements Affect Coagulation in Women Using Birth Control Pills Phase 4
Completed NCT03139097 - Reference Range Study for the Quantra Analyzer With the Quantra Surgical Cartridge
Completed NCT00839995 - Use of ROTEM for Multi-level Spine Surgery N/A
Active, not recruiting NCT02639780 - Biochemical Alterations of Stored Erythrocyte Membranes
Completed NCT00933738 - Evaluation of the Accuracy of the INRatio Prothrombin Time (PT) Monitoring System With a New Test Strip for the Oral Anticoagulation Therapy Patient in the Presence of Heparin and Low Molecular Weight Heparin (e.g., Enoxaparin or Dalteparin) N/A