Coagulation Clinical Trial
Official title:
Multi-site Study for Evaluation of Clinical Ranges of Whole Blood Clotting Times of Patients on Anticoagulants and Verification of Measurement Precision of Liquid Quality Controls With the Perosphere Technologies' PoC Coagulometer
The Perosphere Technologies' PoC Coagulometer measures clotting times of fresh whole blood samples. Clotting is initiated by glass surface activation and terminates on optical detection of fibrin assembly, the final step in the coagulation cascade. Since activation occurs at the top of the intrinsic pathway and detection occurs at the bottom of the final common pathway, the Perosphere Technologies' PoC Coagulometer has shown sensitivity to a broad range of drugs and reagents that affect blood clotting processes, including the Direct Oral Anticoagulants, DOACs (e.g. rivaroxaban, apixaban, and edoxaban), as well as the heparins (e.g. enoxaparin, a low molecular weight heparin, and unfractionated heparin). The purpose of the present study is to characterize the performance of the PoC Coagulometer measuring Clotting Time Controls, as well as fresh whole blood from both healthy volunteers and DOAC patients at three field testing sites.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03255187 -
Effect of Dietary Supplemental Fish Oil in Alleviating Health Hazards Associated With Air Pollution
|
N/A | |
| Completed |
NCT02239744 -
Intervention Study on the Health Impact of Air Filters in Chinese Adults
|
N/A | |
| Completed |
NCT00143715 -
Oral Vitamin K for Warfarin Associated Coagulopathy
|
Phase 3 | |
| Completed |
NCT00794755 -
Low Dose Supplementation to Improve Anticoagulation Control With Oral Vitamin K as an Adjuvant to Warfarin Therapy
|
Phase 3 | |
| Not yet recruiting |
NCT05865691 -
Role of Coagulation, Inflammation and Vessels in Chronic Liver Disease
|
||
| Enrolling by invitation |
NCT06415760 -
Reference Range Study for the Quantra System With the QStat Cartridge in Obstetric Patients
|
||
| Recruiting |
NCT04377490 -
Thrombo Embolic Events in Hospitalized Patients With Covid-19 Serious Acute Pneumopathy
|
||
| Recruiting |
NCT04299828 -
Evaluation of Pro-Inflammatory Leukocyte Activity in Patients Undergoing Cardiac Surgery
|
||
| Withdrawn |
NCT01121510 -
Hemostatic Closure of Femoral Artery Access Site, Using the QuickClose Design 9 System
|
Phase 1/Phase 2 | |
| Completed |
NCT04746391 -
Impact of Clotting on Dialyzer Efficiency
|
N/A | |
| Completed |
NCT03820401 -
Dialysis Performance of Different Dialyzer Membranes Using Different Coagulation Strategies
|
N/A | |
| Completed |
NCT05998421 -
The Effects of Acupuncture on the Natural Pregnancy in Patients With Recurrent Abortion
|
N/A | |
| Terminated |
NCT00909298 -
Left Ventricular Assist Device (LVAD) Specialized Centers of Clinically Orientated Research (SCCOR) Coagulation - Acute Intrinsic Pathway Antagonist (IPA)
|
Phase 2 | |
| Completed |
NCT02339415 -
Targeted Anticoagulation Therapy to Reduce Inflammation and Cellular Activation in Long-term HIV Disease
|
Phase 2 | |
| Terminated |
NCT01428102 -
RapidTEG MA Validation
|
N/A | |
| Completed |
NCT00990158 -
Does Low Dose Oral Vitamin K Improve International Normalized Ratio (INR) Stability?
|
Phase 3 | |
| Completed |
NCT00705991 -
Validation of Thrombelastometry (ROTEM®)
|
Phase 4 | |
| Completed |
NCT05166824 -
Clinical Study To Assess The Safety, Parameters And Efficacy For Procedures Using A Radiofrequency Device
|
N/A | |
| Completed |
NCT03418363 -
How DHEA Supplements Affect Coagulation in Women Using Birth Control Pills
|
Phase 4 | |
| Completed |
NCT03139097 -
Reference Range Study for the Quantra Analyzer With the Quantra Surgical Cartridge
|