Coagulation; Intravascular Clinical Trial
Official title:
Randomized Comparison of Continuous and Intermittent Heparin Infusion During Catheter Ablation of Atrial Fibrillation
Optimal anticoagulation using heparin with close attention to maintain therapeutic dosing
during the procedure is important.
Randomized comparison of continuous and intermittent heparin infusion during catheter
ablation of Atrial Fibrillation.
Intravenous heparin was used during the procedure to prevent catheter-induced thrombosis.
heparin is administered during the procedure to achieve recommended activation clotting
times (ACT) values, typically >300 seconds to prevent thromboemboli during the procedure.
Most of the practitioners was that ACT level should be checked at 30- to 60-minute intervals
and then have injected intermittently.
intermittent heparin infusion, concentration is great changed because the heparin has
30minutes half-period.
researchers postulate that a constant therapeutic concentrations would be beneficial to
continuous infusion than intermittent infusion.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
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