Kidney Transplant; Complications Clinical Trial
Official title:
Historical Controlled, Single Center Open Label Pilot Comparing the Effectiveness and Tolerability of De-novo Initiation of Letermovir Versus Valganciclovir for Cytomegalovirus Prophylaxis in AA Kidney Transplant Recipients
CMV viremia will be treated with either oral valganciclovir, intravenous ganciclovir or alternative agents, according to AST ID COP (American Society of Transplantation Infectious disease community of practice) guidelines.
Intervention: Letermovir prophylaxis. Prophylaxis is once daily dose of Letermovier starting Day 1 of post-transplant up until 6 months post-transplant. Participants enrolled in this study will also receive prophylactic acyclovir 400mg twice daily for the duration of their Letermovir treatment. Strategy for CMV Viremia: CMV viremia will be treated with either oral valganciclovir, intravenous ganciclovir or alternative agents, according to AST ID COP (American Society of Transplantation Infectious disease community of practice) guidelines. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04369456 -
Blood Biomarkers as Predictors of COVID-19 Disease Progression in Recently Infected Kidney Transplant Patients
|
N/A | |
Withdrawn |
NCT04560582 -
Immunosuppression Reduction in Failed Allograft Guided by cfDNA
|
||
Not yet recruiting |
NCT05782543 -
Renal Ex Vivo Warm Advanced Resuscitation Through Machine Perfusion
|
N/A | |
Completed |
NCT03996551 -
ExeRTiOn2- The Weight Gain Prevention Exercise in Renal Transplant Online Study
|
N/A | |
Recruiting |
NCT05081141 -
HHV8 and Solid Organ Transplantation
|
||
Recruiting |
NCT04508907 -
A Study to Evaluate Preemptive Therapy in Hepatitis C (HCV) Organ Transplant Recipients
|
Phase 4 | |
Recruiting |
NCT06440330 -
Define Predictors for Posttransplant Diabetes Mellitus Study
|
||
Not yet recruiting |
NCT06025240 -
Expanding the Scope of Post-transplant HLA-specific Antibody Detection and Monitoring in Renal Transplant Recipients
|
||
Recruiting |
NCT04713774 -
Bone Density and Vascular Calcifications Evolution After Renal Transplant
|
||
Active, not recruiting |
NCT05483725 -
Immunological Safety and Effectiveness of the First Booster Dose of mRNA Vaccines Against COVID-19 in Kidney Transplant Recipients.
|
||
Recruiting |
NCT06095492 -
Effect of Empagliflozin vs Linagliptin on Glycemic Outcomes,Renal Outcomes & Body Composition in Renal Transplant Recipients With Diabetes Mellitus
|
N/A | |
Active, not recruiting |
NCT04207177 -
Immunosuppressive Drugs and Gut Microbiome: Pharmacokinetic- and Microbiome Diversity Effects
|
Phase 4 | |
Recruiting |
NCT03410654 -
Assessment of Cognitive Function Before and After Conversion From Immediate Release Tacrolimus to Envarsus XR.
|
Early Phase 1 | |
Completed |
NCT03373266 -
Serun Fluoride and Kidney Transplant
|
Phase 2 | |
Completed |
NCT04835948 -
Efficacy of Single Dose Anti-thymocyte Globulin in the Modulation of T Lymphocytes in Kidney Transplantation
|
||
Not yet recruiting |
NCT04514666 -
VOCs in Kidney and Liver Transplants
|
N/A | |
Recruiting |
NCT03373500 -
Effect of Dietary Salt Reduction on Blood Pressure in Kidney Transplant Recipients
|
N/A | |
Recruiting |
NCT05900401 -
Delayed Tolerance Through Mixed Chimerism
|
Phase 1/Phase 2 | |
Not yet recruiting |
NCT05166460 -
Novel Cooling Device for the Elimination of Warm Ischemia During Renal Transplantation
|
N/A | |
Recruiting |
NCT05977387 -
Pediatric Kidney Transplant
|