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Cleft Palate clinical trials

View clinical trials related to Cleft Palate.

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NCT ID: NCT04909619 Enrolling by invitation - Clinical trials for Cleft Palate Children

Suprazygomatic Maxillary Nerve Block in Cleft Palate Outcomes

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

Increased pain after cleft palate surgery is the leading cause of increased hospital length of stay, delayed oral intake, readmission, and respiratory compromise. The goal is to improve all outcomes by identifying the most effective evidenced-based method of intra-operative pain control.

NCT ID: NCT04725370 Completed - Clinical trials for Cleft Lip and Palate

Characterization of Cleft Lip and Palate Conditions in Guatemala

Start date: October 30, 2017
Phase:
Study type: Observational

The purpose of this study is to compare types of and risk factors for cleft lip and palate in a Guatemalan population to a United States population.

NCT ID: NCT04718558 Completed - Cleft Palate Clinical Trials

Optic Nerve Sheath Diameter Measurement in Cleft Palate Repair

Start date: October 1, 2020
Phase:
Study type: Observational [Patient Registry]

The aim of this study is to evaluate the effect of the Boyle-Davis mouth opener, which is routinely used in cleft palate surgery, on intracranial pressure by USG-guided optic nerve sheath diameter measurement, which is a non-invasive method with proven effectiveness and reliability in recent years.

NCT ID: NCT04683978 Completed - Cleft Palate Clinical Trials

Effect of Neck Extension on Intraocular Pressure in Patients Undergoing Palatoplasty

Start date: February 10, 2021
Phase:
Study type: Observational

The purpose of this study is to investigate the change in intraocular pressure according to the neck extension during palatoplasty in pediatric patients.

NCT ID: NCT04616690 Completed - Clinical trials for Cleft Lip and Palate

Three-dimensional Cleft Lip and Palate Morphology Prior to One-stage Cleft Repair

Start date: December 7, 2020
Phase:
Study type: Observational [Patient Registry]

This is a prospective observational cohort study of consecutive patients with cleft lip and palate deformity undergoing cleft repair at the Institute of Mother and Child in Warsaw. Cleft morphology will be captured with photo and intraoral camera before routine surgery at around 8 months. Furthermore, wound healing at 3 months postoperative will be assessed.

NCT ID: NCT04489680 Completed - Cleft Palate Lip Clinical Trials

Cleft Palate Surgical Simulator: Improvement in Surgical Trainees' Knowledge and Confidence.

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

Trainees' experience in cleft surgery is limited due to the high-risk nature of the surgery and centralization of cleft care. Simulations allow trainees to learn complex surgical skills whilst ensuring patient safety. Existing cleft surgical simulators are over-simplified or prohibitively expensive. We developed and tested a high-fidelity yet cost-effective simulator for cleft palate repair. Skeletal elements were obtained through high-resolution scanning of a pathologic specimen, 3D printed and then molded in plastic. Soft tissue components were formed through molding layers of silicone. 26 UK specialty trainees performed a vomerine mucosal flap and intra-velar veloplasty in a one-hour workshop. Pre- and post-simulation questionnaires assessing cleft knowledge and surgical confidence were compared for statistical significance.

NCT ID: NCT04478201 Recruiting - Clinical trials for Obstructive Sleep Apnea

Comparing the Side-lying Sleep Positioning to Back-lying in Infants With Cleft Palate

SLUMBRS2
Start date: January 28, 2022
Phase: N/A
Study type: Interventional

The craniofacial abnormalities found in infants and children with cleft palate (CP) lead to increased risk of obstructive sleep apnoea (OSA). In children and adults sleep position is known to influence the patency of the airway during sleep. Altering sleep position in infants with CP may offer a 'low-cost, high impact' intervention to limit the negative impacts of OSA on child development. Children with CP are at increased risk of impairment in learning, memory and cognition, with OSA representing an additional risk to cognitive development. Infants with CP are at risk of poor weight gain and 'failure to thrive', which can be further exacerbated by co-existing OSA. The design and conduct of the proposed randomised controlled trial will benefit from lessons learned from both the feasibility and other previous studies. Investigators demonstrated that existing advice given about sleep position varied significantly with some centres recommending back-lying and others side-lying. Sample size calculations were based on this multi-source data. Parents in the feasibility study knew that sleep position advice for infants with CP changes regularly. They understood why not adhering to 'national guidance' (DoH 2009, Back to Sleep) could be necessary as their infants are "different to normal infants". How will this study benefit infants with cleft palate and their parents? The proposed study will eliminate the current uncertainty and variability in advice provided to parents of infants with CP, whilst potentially limiting the negative impact of OSA on development. This work has been prioritised and received unanimous support from Cleft Lip and Palate Association (CLAPA), Craniofacial Society Great Britain and Ireland (CFSGBI) and Clinical Nurse Specialists. Aim.To determine the clinical effectiveness in infants with CP of side-lying as compared to back-lying sleep positioning in reducing oxygen desaturation resulting from OSA.

NCT ID: NCT04467463 Recruiting - Postoperative Pain Clinical Trials

Peripheral Nerve Block Techniques During Cleft Palate

Start date: November 1, 2020
Phase: N/A
Study type: Interventional

Regional blocks are commonly used in pediatric anesthesia to achieve adequate postoperative analgesia. Suprazygomatic Maxillary nerve block (SMN) and Greater Palatine nerve block (GPN) are regional blocks described for use during cleft palate (CP) repair surgery.The aim of this study was to compare the analgesic effect as well as the incidence of complications associated with the use of bilateral GPN and bilateral SMN blocks in children undergoing palatoplasty surgery.

NCT ID: NCT04367961 Completed - Deafness Clinical Trials

Auditory Profile and Language Development in Children Operated for Cleft Palate

VELAUDI
Start date: March 11, 2020
Phase:
Study type: Observational

Observational study about children with cleft palate from surgery to pre-adolescence :Description of language development and hearing profile.

NCT ID: NCT04366674 Completed - Cleft Palate Clinical Trials

Mordified Restoration of Tensor Veli Palatini in Cleft Palate Repair

Start date: January 1, 2013
Phase: N/A
Study type: Interventional

to study the benefical audiological and/or otological effect by mordified restoration of tensor veli palatini in cleft palate repair compared to traditional Langenbeck's repair and merely levator veli palatini restoration.