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NCT06088134 Clinical Trial

Contrast-enhanced CT-based Deep Learning Model for Preoperative Prediction of Disease-free Survival (DFS) in Localized Clear Cell Renal Cell Carcinoma (ccRCC)

Clear Cell Renal Cell Carcinoma Clinical Trial

Official title:
Urology Department of the First Affiliated Hospital of Chongqing Medical University

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT06088134
Other study ID # DL-ccRCC
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date September 1, 2022
Est. completion date August 1, 2024

Study information
Verified date February 2024
Source First Affiliated Hospital of Chongqing Medical University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This study aims to preoperatively predict DFS of patients with localised ccRCC using a deep learning prognostic model based on enhanced contrast CT images, validate it's predictive ability in multicentre data and compare it's predictive ability with traditional models.

Recruitment information / eligibility
Status Recruiting
Enrollment 800
Est. completion date August 1, 2024
Est. primary completion date March 1, 2024
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria: - underwent partial/radical nephrectomies - histologically diagnosed as ccRCC - with complete clinical data and preoperative CT image data Exclusion Criteria: - with incomplete clinic-pathological data - lack of preoperative contrast-enhanced CT images or the image quality was unsuitable for analysis - who received pre-surgery neoadjuvant or adjuvant therapies - with multiple renal tumors or/and had synchronous metastasis

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
China Yingjie Xv Chongqing Chongqing

Sponsors (1)
Lead Sponsor Collaborator
Mingzhao Xiao

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary disease-free survival (DFS) the interval from the date of surgery to disease recurrence, all-cause mortality or the last visit recruitment occurred between June 2013 and March 2020
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