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Claudication, Intermittent clinical trials

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NCT ID: NCT06448390 Recruiting - Clinical trials for Claudication, Intermittent

Exercise Training Study of Patients With Claudicatio Intermittens

Start date: January 1, 2024
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate whether walking capacity in patients with intermittent claudication is improved more by home-based 5+ exercise training than by current recommendations of daily walking.

NCT ID: NCT06082466 Recruiting - Clinical trials for Peripheral Arterial Occlusive Disease

FRAMED Infrainguinal Venous Bypass Versus Conventional Autologous Bypass Trial

Framed IVB
Start date: September 11, 2023
Phase: N/A
Study type: Interventional

The purpose of this clinical trial is to analyze patency after autologous infrainguinal bypass surgery in patients receiving a venous conduit versus a covered venous conduit.

NCT ID: NCT06056193 Active, not recruiting - Clinical trials for Peripheral Arterial Occlusive Disease

The SIR-POBA Bypass Trial

Start date: September 20, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare plain old balloon angioplasty with sirolimus-coated balloon angioplasty in patients with an infrainguinal venous bypass stenosis. The main question we aim to answer is, how patency is affected by each of the randomised treatment options.

NCT ID: NCT06041880 Not yet recruiting - Clinical trials for Peripheral Artery Disease

Passive Calf Stretching Therapy in Peripheral Artery Disease

Start date: April 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to assess the effects of passive calf muscle stretching in patients diagnosed with peripheral artery disease (PAD). The main question it aims to answer are: 1. To determine if daily calf muscle stretching at home improves calf muscle and vascular health. 2. To determine if daily calf muscle stretching at home improves walking performance. Participants will use inflatable ankle splints for 30 minutes a day, 5 days a week for 4-weeks on both days and 4-weeks of no stretching.

NCT ID: NCT06007469 Not yet recruiting - Clinical trials for Critical Limb Ischemia

Pedal Acceleration Time (PAT) as a Measure of Foot Perfusion

PAT
Start date: October 4, 2023
Phase:
Study type: Observational [Patient Registry]

To identify a correlation between Toe Brachial pressure Index (TBPI) and Acceleration time of the pedal vessels. The aim would then to use this data to design a clinical study assessing the relationship between PAT and wound healing in patients with PAD.

NCT ID: NCT05794932 Recruiting - Venous Thromboses Clinical Trials

Exercise Tolerance After Venous Recanalization for Post-thrombotic Syndrome

ETERecaVSPT
Start date: April 17, 2023
Phase: N/A
Study type: Interventional

Post-thrombotic syndrome (PTS) is the most frequently observed chronic complication of deep vein thrombosis (DVT), with an estimated cumulative incidence of 20-50%. Endovascular venous recanalization with angioplasty and stenting of obstructive lesions is the recommended treatment option to reduce or correct the symptoms of DVT. However, its impact on the physical capacity and breathlessness of patients has not been fully demonstrated. The heterogeneous evidences of clinical improvement is probably related to the presence or absence of collateral veins developed in these patients with proximal venous obstruction (iliac or iliofemoral with or without inferior vena cava involvement), which ensure the cardiac venous return. The aim of this study is to compare changes in maximal oxygen uptake after endovascular venous recanalization in DVT patients and to evaluate the hemodynamic, respiratory and muscular improvement induced by the restoration of venous flow in the occluded segments.

NCT ID: NCT05587465 Recruiting - Clinical trials for Claudication, Intermittent

Evaluation of Safety and Effectiveness of Lobster Dynamic Interspinous Spacer in Lumbar Spinal Stenosis

LB2CT01
Start date: October 5, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to demonstrate the safety and effectiveness of the Lobster interspinous spacer device for the treatment of Lumbar Spinal Stenosis in comparison to an SSED-based performance goal.

NCT ID: NCT04925219 Recruiting - Clinical trials for Peripheral Arterial Disease

REmotely Supervised Exercise Therapy Trial 2

RESET2
Start date: June 1, 2021
Phase: N/A
Study type: Interventional

Supervised exercise for intermittent claudication is a first line therapy for peripheral arterial disease, as recommended by the National Institute for Health and Clinical Excellence and the European Society for Vascular Surgery. However 2/3 of British trusts cannot implement this due to gym availability, costs, travel time and the requirement for social distancing. During the COVID-19 lockdown the investigators successfully performed a feasibility study for remotely supervised exercise using an electronic walking log and fortnightly video calls with a physiotherapist. RESET2 aims to compare the benefits of and adherence to remotely supervised exercise with self-directed exercise to absolute walking distance.

NCT ID: NCT04832308 Withdrawn - Clinical trials for Peripheral Artery Disease

Mobile Intervention Supervised Exercise Therapy Study 1

MiSET-1
Start date: August 20, 2021
Phase: N/A
Study type: Interventional

This is a randomized controlled trial evaluating the impact of the mobile phone delivered SVS SET Program on utilization, functional capacity, symptoms and quality of life.

NCT ID: NCT04800692 Recruiting - Clinical trials for Peripheral Artery Disease

The Effects of ATLAS Therapy on Nitric Oxide Bioavailability in Patients With Intermittent Claudication

ATLAS
Start date: June 15, 2021
Phase: Phase 1
Study type: Interventional

This study will focus on people with claudication from peripheral arterial disease. The investigators are researching whether a multicomponent therapeutic can increase the production of Nitric Oxide in the blood and whether that leads to an improvement in pain free walking distance and overall physical activity.