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Churg-Strauss Syndrome (CSS) clinical trials

View clinical trials related to Churg-Strauss Syndrome (CSS).

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NCT ID: NCT03482479 Recruiting - Clinical trials for Giant Cell Arteritis

Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis

LoDoNaVasc
Start date: February 4, 2019
Phase: Phase 2
Study type: Interventional

Naltrexone is an FDA approved drug (for alcoholism) that has found widespread use "off-label" to treat pain and improve quality of life at much lower doses than are used for the approved indication. There are a few scientific studies in three conditions (fibromyalgia, Crohn's disease, and multiple sclerosis) that suggest that this drug has benefit and is safe. However, considering the extent of use in other conditions, and uncertainty about the mechanism of action study is needed in a diverse set of diseases, including vasculitis. The purpose of this clinical trial is to determine if low dose naltrexone is effective in improving health-related quality of life (HRQoL) among patients with vasculitis. Although it is a pilot study, a placebo-controlled component is used because of the prominent placebo group effect seen in studies with self-reported subjective outcomes.

NCT ID: NCT02593565 Recruiting - Vasculitis Clinical Trials

Vasculitis Pregnancy Registry

V-PREG
Start date: November 2015
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to learn about the experience of women with vasculitis who become pregnant. In particular, the study will consist of several online surveys to assess 1. each woman's vasculitis severity and pregnancy-related experiences, and 2. pregnancy outcomes.