Neural Mobilization With Task Based Activities on Upper Limb in Patients With Chronic Stroke.

Chronic Stroke Clinical Trial

Official title:

Combined Effects of Neural Mobilization With Task Based Activities on Spasticity and Motor Function of Upper Limb in Patients With Chronic Stroke.

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06131827
• Other study ID #: REC/RCR &/23/0233
• Status: Recruiting
• Phase: N/A
• Start date: July 17, 2023
• Est. completion date: January 22, 2024

Study information

• Verified date: December 2023
• Source: Riphah International University
• Contact: Memona Ayesha
• Phone: 03129601249
• Email: memonaayesha66[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Stroke is defined as sudden neurological disruption of blood supply to brain. It is most common disease that causes severe disabilities like hemiparesis which is most common motor impairment that leads to persistent upper limb dysfunction. In this study we use two techniques to improve upper limb motor dysfunction and reduce spasticity. One is task-based activities which is used to improve motor function and focus on active participation rather than normal movement pattern and other is neural mobilization which aims to reduce spasticity which is most common in stroke patients.

Description:

This study will be randomized controlled trial. Participants having stroke past 6 month to 1 year and mini mental state examination score >21 will be included in this study. And participants with severe orthopedic deformity, joint pain and visual impairment will be excluded from this study. The sample size will consist of 34 participants selected through non probability convenient sampling technique, which will further be randomized through sealed envelope method and will divide into two groups .Data will be collected using assessment tools, including the Fugl Mayer assessment scale, box and block test and wolf motor function test. 17 Participants will be assigned to the interventional group (A )which will undergo neural mobilization of median nerve with task based activities .Neural mobilization technique will be performed with twenty oscillations per minute being repeated three sets of one minute respecting one minute interval for rest between each set for 4 days weekly for 6 week.

while task based activities will be performed with the dosage of 45 minutes session 5 days weekly for 6 weeks and 17 participants will be assigned to control group (B

)which will undergo only neural mobilization of median nerve and will receive neural mobilization with twenty oscillations per minute being repeated three sets of one minute respecting one minute interval for rest between each set for 4 days weekly for 6 weeks. After applying both interventions motor function improvement and spasticity reduction will be measured by using BBT, wolf motor scale and fugl -Meyer assessment scale and data will be analyzed through sPss Version 25.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 34
• Est. completion date: January 22, 2024
• Est. primary completion date: January 15, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 30 Years to 55 Years

Eligibility

Inclusion Criteria:

• Male and female stroke patients.

• 6 month to one year post stroke .

• Age 30-55

• Stable patients

• Mini - mental state examination>2

• Modified ashworth Scale equal<+1

Exclusion Criteria:

• Orthopedic deformity

• Patients undergo bottulinuminjection toxin injection

• Visual impairments

• Joint pain (elbow, shoulder, wrist)

Related Conditions & MeSH terms

• Chronic Stroke
• Stroke

Intervention

Other:
• Neural mobilization
Neural mobilization will be performed with twenty oscillations per minute being repeated three sets of one minute respecting one minute interval of rest between each set for 4 days weekly for six week
• Task based activities
Task based activities consisted of different types task which will be performed with the dosage of 45 minute session 5 days weekly for six week.

Locations

Country	Name	City	State
Pakistan	Ripha international university	Lahore	Punjab

Sponsors (1)

Lead Sponsor	Collaborator
Riphah International University

Country where clinical trial is conducted

Pakistan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Box and block test	It measures unilateral gross manual dexterity	6 weeks
Primary	Wolf motor Function Test	The Wolf Motor Function Test (WMFT) quantifies upper extremity (UE) motor ability through timed and functional tasks	6 weeks
Primary	Fugl -Meyer assessment scale	It measure motor ability of upper extremity	6 weeks