Chronic Stroke Clinical Trial
Official title:
Utilization of Immersive Virtual Reality in Computerized Script Training for People With Aphasia: A Feasibility Study
The goal of this intervention study is to investigate the effects of immersive virtual reality in rehabilitation of language and communication of individuals with post-stroke aphasia. The main research questions are: 1. Is VR-based script training a feasible treatment to Cantonese-speaking PWA? 2. Will VR-based script training, when compared to conventional script training, better enhance treatment outcomes in functional communication of PWA? Participants will be assessed before, in the middle of, immediately after treatment and 8-week post treatment in terms of their performance on: 1. Accuracy and time for producing trained scripts. 2. Accuracy and time for producing un-trained scripts 3. Standardized aphasia test on severity of language impairment 4. Standardized aphasia test on functional communication The participants will be randomly allocated to receive one of the treatment: 1. Virtual reality-based computerized script training; or 2. Computerized script training without virtual reality Researchers will compare the treatment outcomes of the two treatment conditions and see if treatment with virtual reality would better promote outcomes when compared to training without virtual reality.
Status | Not yet recruiting |
Enrollment | 26 |
Est. completion date | August 2024 |
Est. primary completion date | June 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 30 Years to 80 Years |
Eligibility | Inclusion Criteria: 1. a stroke onset more than six months, with an Aphasia Quotient (AQ) below 96.4, as evaluated by the Cantonese version of Western Aphasia Battery (CAB; Yiu, 1992), 2. premorbid fluent Cantonese speakers, 3. aged between 30 and 80 years, 4. no reported progressive neurogenic disorders such as dementia or Parkinson's disease, 5. no motor speech disorders of moderate to severe level, and 6. normal or corrected-to-normal vision and hearing functions Exclusion Criteria: 1. concurrent participation in other aphasia treatment trials, and 2. incompatibility with immersive VR exposure such as complains of nausea, headache, or other severe discomforts during trial use of a head-mounted device during screening. |
Country | Name | City | State |
---|---|---|---|
Hong Kong | Hong Kong Polytechnic University | Hong Kong | Hong Kong SAR |
Lead Sponsor | Collaborator |
---|---|
The Hong Kong Polytechnic University |
Hong Kong,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Percentage correct in reading aloud the sentences included in the trained scripts | Trained scripts will be shown in written form while the PWA will be asked to read aloud the scripts. | From baseline up to 1-week post training | |
Primary | Time required in read aloud of trained scripts | Total time to read aloud the trained scripts | From baseline up to 1-week post training | |
Primary | Percentage correct in spontaneous production of the sentences included in the trained scripts | No written cue will be provided while the PWA will produce the scripts upon questions. | From baseline up to 1-week post training | |
Primary | Time required for spantaneous production of trained scripts | No written cue will be provided while the PWA will produce the scripts upon questions. | From baseline up to 1-week post training | |
Secondary | CAB | Cantonese version of the Western Aphasia Battery | From baseline up to 1-week post training | |
Secondary | CANELT | Cantonese version of the Amsterdam-Nijmegen Everyday Language Test (ANELT; Blomert et al., 1994) | From baseline up to 1-week post training | |
Secondary | Percentage correct in producing untrained but related scripts | No written cue will be provided while the PWA will produce the untrained scripts that share similar contexts with the trained scripts. | From baseline up to 1-week post training |
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