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Clinical Trial Summary

The purpose of this study is to evaluate the production of MMP in failing hearts.


Clinical Trial Description

Myocardial fibrosis is observed in failing hearts and parallel to the progression of chronic heart failure (CHF) and myocardial remodeling. Matrix metalloproteinases (MMPs) are considered markers of fibrosis. Recently, circulating MMPs can be measured and are elevated in patients with CHF. However, MMPs it is still unclear whether MMPs are produced in failing hearts. Thus, the purpose of this study is to evaluate the production of MMP in failing hearts. ;


Study Design

Observational Model: Case Control, Time Perspective: Prospective


Related Conditions & MeSH terms


NCT number NCT00663494
Study type Observational
Source Tottori University Hospital
Contact
Status Completed
Phase N/A
Start date February 2003
Completion date July 2006

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