Matrix Metalloproteinase (MMP) in Heart Failure

Status Completed

Clinical Trial Summary

The purpose of this study is to evaluate the production of MMP in failing hearts.

Clinical Trial Description

Myocardial fibrosis is observed in failing hearts and parallel to the progression of chronic heart failure (CHF) and myocardial remodeling. Matrix metalloproteinases (MMPs) are considered markers of fibrosis. Recently, circulating MMPs can be measured and are elevated in patients with CHF. However, MMPs it is still unclear whether MMPs are produced in failing hearts. Thus, the purpose of this study is to evaluate the production of MMP in failing hearts. ;

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00663494
Study type	Observational
Source	Tottori University Hospital
Contact
Status	Completed
Phase	N/A
Start date	February 2003
Completion date	July 2006

View Details

See also
Status	Clinical Trial	Phase
Terminated	`NCT03346278` - Text Message Intervention to Improve Cardiac Rehab Participation	N/A
Completed	`NCT02696967` - A Study of CLR325 in Chronic Stable Heart Failure Patients.	Phase 2
Recruiting	`NCT03834155` - Enhancing Cardiac Rehabilitation Through Behavioral Nudges	N/A
Withdrawn	`NCT04507347` - Efficacy and Safety of TRC041266 in Patients With Heart Failure, LVEF ≥40%, Diastolic Dysfunction and Type 2 Diabetes Mellitus	Phase 3
Completed	`NCT02204449` - Cardiac Rehabilitation Peer Mentorship	N/A
Completed	`NCT00664222` - Spironolactone and Insulin Resistance in Chronic Heart Failure (CHF)	Phase 4
Completed	`NCT00663195` - Effects of Spironolactone on Matrix Metalloproteinases (MMPs) in Heart Failure	Phase 4
Recruiting	`NCT05034549` - Noninvasive Ventilation for Chronic Heart Failure	N/A
Recruiting	`NCT01065194` - Efficacy and Safety of Pulsed Infusions of Levosimendan in Outpatients With Advanced Heart Failure	Phase 3