Chronic Rhinosinusitis Clinical Trial
Official title:
The Sinonasal Outcome Test - 22, Validated for Danish Patients
Introduction: Chronic rhinosinusitis (CRS) is a significant health problem increasing in
both incidence and prevalence. It calls into attention consensus about diagnosing, assessing
symptoms and treatment of patients with CRS. Therefore a validated Danish measure of
health-related quality of life in sinonasal disease is needed.
Method: The Sinonasal Outcome measure 22 (SNOT-22) was translated into Danish and
reproducibility was evaluated by test-retesting 40 patients with CRS. The statistical
analyses used, were Pearson´s correlation coefficient, Cronbach´s alfa, Kappa and
Bland-Altman´s Plot. Reproducibility was also tested looking at subscales within the
SNOT-22.
Result: The results show good internal correlation with Cronbach´s alfa at 0.83 in the
initial test and 0.92 in the retest. Pearson was 0.70 (p<0.001) revealing good correlation
between the initial scores and the retests scores. Kappa was calculated for each item with a
mean value of 0.61 showing substantial agreement. Paired t-test revealed no significant
difference in the subscales.
Conclusion: The Danish version of SNOT-22 is recommended for Danish clinicians and
researches as a patient-reported measure of outcome in sino-nasal disorders such as
rhinosinusitis and nasal polyposis.
Status | Completed |
Enrollment | 44 |
Est. completion date | March 2009 |
Est. primary completion date | March 2009 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 15 Years to 75 Years |
Eligibility |
Inclusion Criteria: Persons diagnosed with Chronic Rhinosinusitis - Exclusion Criteria: Change of treatment or acute change of symptoms due to common cold/influenza in the time between completing the test and the retest. If SNOT-score was very low. Persons who left before offered test or declined testing. |
Observational Model: Cohort, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
Denmark | Department of Otorhinolaryngology, Odense University Hopsital | Odense |
Lead Sponsor | Collaborator |
---|---|
Odense University Hospital |
Denmark,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Reproducibility of Sinonasal Outcome test 22 | From the time of fullfilling the first SNOT-22 to fullfilling the second SNOT-22 after 14 days | No |
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