Chronic Rhinosinusitis Clinical Trial
Official title:
The Sinonasal Outcome Test - 22, Validated for Danish Patients
Introduction: Chronic rhinosinusitis (CRS) is a significant health problem increasing in
both incidence and prevalence. It calls into attention consensus about diagnosing, assessing
symptoms and treatment of patients with CRS. Therefore a validated Danish measure of
health-related quality of life in sinonasal disease is needed.
Method: The Sinonasal Outcome measure 22 (SNOT-22) was translated into Danish and
reproducibility was evaluated by test-retesting 40 patients with CRS. The statistical
analyses used, were Pearson´s correlation coefficient, Cronbach´s alfa, Kappa and
Bland-Altman´s Plot. Reproducibility was also tested looking at subscales within the
SNOT-22.
Result: The results show good internal correlation with Cronbach´s alfa at 0.83 in the
initial test and 0.92 in the retest. Pearson was 0.70 (p<0.001) revealing good correlation
between the initial scores and the retests scores. Kappa was calculated for each item with a
mean value of 0.61 showing substantial agreement. Paired t-test revealed no significant
difference in the subscales.
Conclusion: The Danish version of SNOT-22 is recommended for Danish clinicians and
researches as a patient-reported measure of outcome in sino-nasal disorders such as
rhinosinusitis and nasal polyposis.
n/a
Observational Model: Cohort, Time Perspective: Prospective
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