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Treatment of Eosinophilic Chronic Rhinosinusitis Utilizing Betamethasone Dipropionate Nasal Cream — OT-007  

Chronic Rhinosinusitis (Diagnosis) Clinical Trial

Official title:
The Effect of Betamethasone Dipropionate on Patients With Eosinophilic Chronic Rhinosinusitis

Clinical Trial Summary

This is an open-label, single dose, pilot study, to assess the efficacy and safety of Betamethasone Dipropionate Nasal Cream 0.0644% (equivalent to 0.05% Betamethasone) for the treatment of eosinophilic Chronic Rhinosinusitis (eCRS).

Clinical Trial Description

In this open-label study, a single dose of the corticosteroid Betamethasone Dipropionate Nasal Cream 0.0644% (equivalent to 0.05% Betamethasone) will be administered under endoscopic guidance to the sinus mucosa of post-FESS patients whose eCRS condition is suboptimal under the current standard of care. The safety and benefits of this treatment will be monitored by patient-reported symptoms and visualization of the sinus mucosa. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05220293
Study type Interventional
Source Oticara Australia PTY LTD
Contact
Status Terminated
Phase Phase 1/Phase 2
Start date February 23, 2022
Completion date December 30, 2023
View Details
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