Clinical Trials Logo
  1. Home
  2. Chronic Respiratory Failure
  3. NCT03473171
  4. Details
NCT03473171 Clinical Trial

Implementation of Nasal Non-Invasive Ventilation With a RAM Cannula in the Inpatient /Outpatient Setting

Chronic Respiratory Failure Clinical Trial

Official title:
Implementation of Nasal Non-Invasive Ventilation With a RAM Cannula in the Inpatient /Outpatient Setting

Clinical Trial Details — Status: Terminated

Administrative data
NCT number NCT03473171
Other study ID # HSC-MS-17-0708
Secondary ID
Status Terminated
Phase N/A
First received
Last updated
Start date June 27, 2016
Est. completion date May 13, 2019

Study information
Verified date March 2020
Source The University of Texas Health Science Center, Houston
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The purpose of this study is to implement a standardized protocol to initiate nasal non-invasive ventilation with RAM nasal cannula (NIV/RAM-NC) with Trilogy mechanical ventilator at Children Memorial Hospital inpatient and outpatient sites, as well as to explore the side effects and complications associated with the use of NIV/RAM-NC in children.

Recruitment information / eligibility
Status Terminated
Enrollment 5
Est. completion date May 13, 2019
Est. primary completion date May 13, 2019
Accepts healthy volunteers No
Gender All
Age group N/A to 21 Years
Eligibility Inclusion Criteria:

- Children admitted to the Children Memorial Hermann Hospital and consulted to Pediatric Pulmonary Service for initiation of NIV/RAM-NC both at the inpatient and outpatient sites.

- Children who fail to wean from chronic respiratory support (CPAP, BiPAP, HFNC) in whom long-term ventilation is considered between 10/2016 - 10/2017 will be included.

Exclusion Criteria:

- Children with minimal setting (CPAP < 5cmH2O, HFNC < 3LPM) able to be weaned to regular nasal cannula.

- Patients with upper airway obstruction that may be candidates for surgical procedure will be excluded.

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• Nasal non-invasive ventilation with RAM cannula
Pediatric Pulmonary Team will be consulted on inpatient or outpatient patients that fail to wean from chronic respiratory support (CPAP, BiPAP, High flow Nasal Cannula) in whom long-term ventilation is considered. Pediatric Pulmonary Team, as a consultant, will consider patient history, physical examination, previous imaging and laboratories and previous attempts to wean from respiratory support and causes of failure to wean. The Pulmonary team will determine which patients would potentially benefit from use of NIV/RAM-NC for long-term respiratory support and will recommend initiation of NIV/RAM-NC.

Locations
Country Name City State
United States The University of Texas Health Science Center at Houston Houston Texas

Sponsors (1)
Lead Sponsor Collaborator
The University of Texas Health Science Center, Houston

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Feasibility as Assessed by Number of Participants Who Had Complications Complications include respiratory failure, tachypnea, hypercapnia, hypoxemia, air trapping or hyperexpansion. 7 days after starting the RAM cannula
See also
  Status Clinical Trial Phase
Completed NCT05084976 - Parental Perception of COVID-19 Vaccine in Technology Dependent Patients
Not yet recruiting NCT05756387 - Improving Chronic Nocturnal Noninvasive Ventilation: a Multimodality Approach
Enrolling by invitation NCT04208581 - Yiqi Huoxue Huatan Granule for Reducing Mortality in COPD With Chronic Respiratory Failure Phase 3
Recruiting NCT02260583 - Effect of Extracorporeal CO2 Removal in Stable Hypercapnic COPD Patients N/A
Completed NCT01255111 - Adaptation to Nocturnal Noninvasive Ventilation in Patients With Chronic Respiratory Failure (ROOMILA) N/A
Active, not recruiting NCT03499470 - Structured Discharge and Follow-up Protocol for COPD Patients Receiving LTOT and NIV N/A
Completed NCT04143230 - Identification of In-hospital Patients in Need of Palliative Care Using a New Simplified Screening Tool N/A
Terminated NCT00208078 - Effect of Non-Invasive Ventilation in Cystic Fibrosis Patient With Chronic Respiratory Failure. Phase 4
Recruiting NCT06286917 - Initiation of Noninvasive Ventilation in ALS Patients With Chronic Respiratory Insufficiency N/A
Completed NCT02342899 - Cost Effectiveness of Outpatient Set-up of Automated NIV in Obese Patients With Chronic Respiratory Failure Phase 3
Not yet recruiting NCT05258370 - Fibroblast Growth Factor 23 in Chronic Respiratory Failure
Completed NCT02804243 - The Efficacy of Nasal High Flow Oxygen Therapy With Rehabilitation in the Patients With Chronic Respiratory Failure N/A
Completed NCT01479959 - Impact of Patient Controlled Positive End-expiratory Pressure on Speech in Tracheostomized Ventilated Patients N/A
Completed NCT01090986 - Home Mechanical Ventilation Effectiveness and Air Leaks N/A
Completed NCT00698958 - Ambulatory Adaptation to Non-Invasive Mechanical Ventilation Phase 4
Not yet recruiting NCT06119087 - Mechanical Insufflation in the Philadelphia Amyotrophic Lateral Sclerosis Cohort (MI-PALS) Study N/A
Recruiting NCT05796297 - Clinical Impact of Patient-ventilator Asynchrony
Recruiting NCT04481295 - Study on Optimal Oxygen Concentration During Pulmonary Rehabilitation N/A
Withdrawn NCT05379439 - Family Connections N/A
Terminated NCT03809832 - Microbiologic Contamination of Home Non Invasive Ventilators