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Is Optimal Minute Ventilation a Predictor of Weaning in Patients With Prolong Mechanical Ventilation?

Chronic Respiratory Failure Clinical Trial

Official title:
Taipei Tzu Chi Hospital , Buddhist Tzu Chi Medical Foundation

Clinical Trial Summary

1. purpose of study: optimal minute could be the prediction of successful weaning and become the new weaning parameter.

2. study design: inclusion criteria: investigators will perform this study at our respiratory care center. Patients who had been maintained on mechanical ventilator in excess of 3 weeks before respiratory care center admission and all previous weaning attempts had ailed.

Exclusion criteria: Patients do not have spontaneous breath. Terminal cancer stage and unstable hemodynamics condition.

3. study duration: 2016/01/01~12/31

Clinical Trial Description

Investigators will preform this study at our respiratory care center. Initially, Investigators collected all physiological parameters and baseline characteristics of patients with prolong mechanical ventilator. Investigators use Gold-Galileo ventilator and patients use adaptive support ventilation mode. In adaptive support ventilation, the clinician enters a target minute volume , using a parameter called minute ventilation percentage. The minute ventilation percentage setting be initially set at 100% (the 100%minute ventilation setting), which provides a target minute ventilation of 0.1 L/min/kg of ideal body weight . Investigators observed respiratory frequency of patients, the minute ventilation percentage was increased every 5 min until the mandatory breath began to appear and spontaneous rate is zero. If the minute ventilation percentage had exceeded 250%, but patients do not have mandatory rate appeared, the optimal minute ventilation of the patient is means above 250%. Investigators also measure other weaning parameters. Finally, Investigators analyze the prediction of optimal minute ventilation as a weaning parameter. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03348085
Study type Observational
Source Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Contact
Status Completed
Phase N/A
Start date January 1, 2016
Completion date December 31, 2016
View Details
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