Chronic Renal Insufficiency Clinical Trial
Official title:
MESNA Zur Prophylaxe Der Kontrastmittel-Induzierten Nephropathie
The purpose of this study is to determine wether Mesna could prevent contrast-induced nephropathy
Contrast-induced nephropathy remains a common complication of radiographic precedures.
Pretreatment with Mesna (Sodium 2-mercaptoethane sulfonate) in combination with sodium
chloride is more protective than sodium chloride alone in animal models of acute renal
failure.
The aim of this study is therefore to determine laboratory and clinical benefit of MESNA, as
an adjunct to saline hydration, in patients with known renal impairment receiving contrast
media.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Prevention
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