Dexmedetomidine for Prevention of Chronic Postoperative Pain

Status Not yet recruiting

Clinical Trial Summary

Chronic postoperative pain (CPSP) is common symptom in patients after surgery, seriously affected the quality of life. Accumulating evidences have demonstrated dexmedetomidine can improve chronic pain. However, the prevention of dexmedetomidine on CPSP remain uncertain.

Clinical Trial Description

Chronic postoperative pain (CPSP) is defined as pain persisting at least 3 months after surgery. It is most common in patients who undergoing breast or thoracic surgery. Dexmedetomidine, a adrenergic α2 agonists, can alleviate the postoperative pain 24 h after surgery. In our study, patients were randomly assigned to one of the two group to receive 0.5mg/kg/h infusion dexmedetomidine (Group D, n=57) or normal saline (Group C, n=57). The pain scales were evaluated day 1, day 2, day 3, month 3, month 6 after surgery. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03275207
Study type	Interventional
Source	Zhongda Hospital
Contact	Yang Jian-jun, PhD
Phone	13357739238
Email	yjyangjj@126.com
Status	Not yet recruiting
Phase	Phase 4
Start date	January 1, 2018
Completion date	October 1, 2018

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