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Clinical Trial Summary

There are over 7 million people living with stroke in the United States. Per year, approximately 17,000 Veterans are admitted to the VA for acute stroke. Chronic pain after stroke can occur between 10-50% of stroke survivors. Post-stroke pain (PSP) can lead to further complications in a stroke survivor's recovery. Exercise has improved PSP and associated symptoms such as mobility, fatigue, and quality of life. Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive technique using electromagnetic induction for cortical neurostimulation. The use of rTMS has been explored shown to be effective in treating chronic PSP but is limited in effect duration. Our proposal will test the hypothesis that rTMS is feasible and safe to be paired with exercise. Additionally, the investigators believe a complementary effect can develop to enhance the neurostimulation duration of rTMS.


Clinical Trial Description

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Study Design


Related Conditions & MeSH terms


NCT number NCT04672044
Study type Interventional
Source VA Office of Research and Development
Contact Chen Lin, MD
Phone (205) 933-8101
Email Chen.Lin@va.gov
Status Recruiting
Phase Phase 1
Start date January 14, 2022
Completion date June 30, 2024