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Chronic Pancreatitis clinical trials

View clinical trials related to Chronic Pancreatitis.

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NCT ID: NCT03112759 Completed - Clinical trials for Chronic Pancreatitis

Assessing the Utility of Cognitive Behavioral Therapy for Pain Control in Patients With Chronic Pancreatitis

Start date: September 9, 2017
Phase: N/A
Study type: Interventional

This study will assess cognitive behavioral therapy as an adjunct to conventional symptom control for patients with chronic pancreatitis.

NCT ID: NCT02947087 Completed - Clinical trials for Chronic Pancreatitis

Alpha-1 Antitrypsin (AAT) Enhances Islet Autograft Survival in Patients With Chronic Pancreatitis

Start date: January 11, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

Primary objective: To describe and compare the safety and efficacy of treatment with AAT in chronic pancreatitis patients who undergo total pancreatectomy and islet autotransplantation (TP-IAT).

NCT ID: NCT02868047 Completed - Clinical trials for Chronic Pancreatitis

Establishing Standards for Normal Pancreatic EUS

Start date: September 2010
Phase: N/A
Study type: Observational

There is tremendous variability in regard to provider perception of findings on EUS for chronic pancreatitis. This study performs tandem EUS exams between expert endosonogrpahers to determine the validity of minimal standard criteria.

NCT ID: NCT02849704 Completed - Clinical trials for Chronic Pancreatitis

Fat Malabsorption in Chronic Pancreatitis

Start date: October 13, 2016
Phase: Phase 2
Study type: Interventional

The objective of this study is to evaluate the malabsorption blood test (MBT), stool coefficient of fat absorption (CFA) and stool bomb calorimetry (BC) methods as potential screening or diagnostic tests for reduced exocrine pancreatic function or pancreatic insufficiency (RPF/PI). A further objective is to determine the test responses before and after pancreatic enzyme medication administration (Creon36™) in the patients with chronic pancreatitis (CP).

NCT ID: NCT02802020 Completed - Clinical trials for Chronic Pancreatitis

WallFlex Pancreatic Metal Stent for Pancreatic Duct Strictures

Start date: January 25, 2017
Phase: N/A
Study type: Interventional

To prospectively document the performance of a FCSEMS for treatment of pancreatic duct strictures in patients with painful chronic pancreatitis.

NCT ID: NCT02693093 Completed - Clinical trials for Chronic Pancreatitis

A Dose Ranging Study Evaluating Efficacy and Safety of NI-03

Tactic
Start date: February 24, 2016
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine the safety and efficacy of NI-03.

NCT ID: NCT02577640 Completed - Clinical trials for Chronic Pancreatitis

Dietary Soy Isoflavones In Chronic Pancreatitis

Start date: July 2015
Phase: N/A
Study type: Interventional

Dietary Soy Isoflavones in Chronic Pancreatitis: Investigating the Anti-inflammatory Effects of Food Innovation Science on Gastrointestinal Disease

NCT ID: NCT02567240 Completed - Clinical trials for Chronic Pancreatitis

Carbon Monoxide-Saturated Medium for Islet Isolation

Start date: January 2015
Phase: Phase 1/Phase 2
Study type: Interventional

The goal of this study is to determine whether harvesting islets using carbon monoxide (CO)-saturated mediums can protect islet cell from death after autologous islet transplantation in patients with chronic pancreatitis.

NCT ID: NCT02384018 Completed - Diabetes Clinical Trials

Mesenchymal Stem Cell and Islet Co-transplantation

Start date: December 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to show safety and tolerability to our mesenchymal stromal cells (MSCs) product which will be autologous in nature, expanded using a non-xenogeneic, human component expansion media (pooled human platelet lysate) and delivered fresh. Subsequently, the investigators intend to test whether infusion of MSCs immediately after islet autograft can reduce onset of diabetes and improve glycemic control after total pancreatectomy and islet autotransplantation.

NCT ID: NCT02108509 Completed - Osteoporosis Clinical Trials

Bone Disease in Chronic Pancreatitis: A Complex Phenomenon

Start date: May 5, 2014
Phase:
Study type: Observational

The purpose of this study is to define the prevalence of low bone density (osteopenia/osteoporosis) in patients with chronic pancreatitis. Secondary aims include investigating the prevalence of hypogonadism (low sex hormones) in patients with chronic pancreatitis and determining if hypogonadism and/or use of narcotic pain medications are risk factors for low bone density in this patient population. 1. Hypothesis: Patients with chronic pancreatitis are at increased risk of low bone density (osteopenia/osteoporosis), and hypogonadism (low sex hormone levels) and narcotic pain medication use are independent risk factors for the development of low bone density in this patient population. 2. The outcome measures include: i) Prevalence of low bone density (osteopenia/osteoporosis) in patients with chronic pancreatitis (as determined by DXA scan and fracture history). ii) Prevalence of hypogonadism (low sex hormones) in patients with chronic pancreatitis (as determined by sex hormone levels and clinical history). iii) Identification of hypogonadism and/or opioid use as risk factors for low bone density in patients with chronic pancreatitis (as determined by univariate and multivariate analysis of multiple risk factors). 3. After obtaining written consent from potential subjects, a questionnaire will be performed outlining risk factors for low bone density. Dual X-ray absorptiometry (DXA scan) will be performed to evaluate for low bone density and a blood test will be performed to evaluate for low sex hormones, low levels of vitamin D, and other risk factors for low bone density.