Chronic Pain Syndrome Clinical Trial
Official title:
Ambulatory Infusion of Lidocaine and Ketamine for Management of Chronic Pain: An Observational Prospective Study
Chronic pain is defined as 'an unpleasant sensory and emotional experience associated with
actual or potential tissues damage, or described in terms of such damage". It is estimated
that 1 in 5 Canadians experience chronic pain "Chronic pain is associated with the worst
quality of life compared with other chronic diseases such as chronic lung or heart disease".
Many of these problems are confined to a specific anatomic structure, and can be diagnosed
and treated by injections, physical therapy, surgery, etc. Nonetheless, other individuals
experience a more generalized pain. This condition has also resulted I depressed mood, bad
relations with other people, sleep disturbances and poor quality of life.
The condition is very difficult to manage, and multiple methods have been recommended.
Therapeutic intravenous infusion may be considered as one of these methods. Patients come for
infusions of non-opioid medications under medical supervision and in a scheduled fashion. Two
most commonly used mediation are lidocaine and ketamine.
Even though it is common to use multiple medications with complementary mechanisms of action
to treat pain a combined lidocaine-ketamine infusion has never been studied Therefore, the
purpose of this research study is to determine whether mixture of two medications (ketamine
and lidocaine) infused intravenously 1 time per month for 6 months results in reduction of
pain unpleasantness.
n/a
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