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Clinical Trial Summary

The purpose of this randomized, placebo-controlled double-blind trial is to evaluate the effect of acetazolamide on right heart function at rest in lowlanders with chronic obstructive pulmonary disease (COPD) traveling to high altitude (HA) and developing early signs of altitude-illness.


Clinical Trial Description

This randomized placebo-controlled, double-blind, parallel-design trial will evaluate effect of acetazolamide on right heart function in lowlanders with chronic obstructive pulmonary disease (COPD) travelling to high altitude and developping early symptoms and/or signs of impending altitude-illness. Qualifying participants will be randomized 1:1 to acetazolamide or placebo treatment during their further stay of 2 days at 3'100 m. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04915365
Study type Interventional
Source University of Zurich
Contact Silvia Ulrich, Prof
Phone +41442552220
Email silvia.ulrich@usz.ch
Status Recruiting
Phase Phase 3
Start date May 1, 2021
Completion date December 31, 2023

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