Chronic Obstructive Pulmonary Disease Clinical Trial
Official title:
The Use of Circulating Tumor Cells in Non-Small Cell Lung Cancer: Novel Isolation Methods and Clinical Applications
The purpose of this study is to assess whether the detection of circulating tumor cells (CTC) could be used as a tool to earlier diagnose, more accurately predict treatment response / failure and predict overall survival in non-small cell lung cancer (NSCLC) patients
Lung cancer remains the most common cause of cancer mortality in the world for both men and
women. More than half of patients diagnosed will die within the first year. Given these
concerning facts, we are in need of novel methodologies to diagnose patients at earlier
stages of the disease, more accurately predict treatment response / failure and predict
overall survival.
The use of CTC has been investigated and shown to predict progression free survival and
overall survival in metastatic breast cancer, and recommended as a breast cancer tumor
marker by the American Society of Clinical Oncology. There have also been relationships
between CTC's and survival, shown in metastatic colorectal and prostate cancer. However,
CTC's have not been thoroughly investigated in non-small cell lung cancer. This trial will
assess if the detection of circulating tumor cells could be used as a tool to help further
advance treatment for NSCLC patients.
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Observational Model: Cohort, Time Perspective: Prospective
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