Chronic Obstructive Pulmonary Disease Clinical Trial
Official title:
A Comparison of Intravenous Versus Oral Administration of Prednisolone in the Treatment of Exacerbations of Chronic Obstructive Pulmonary Disease
Treatment with systemic corticosteroids for acute exacerbations of COPD results in the
improvement of clinical outcomes. The optimal route of administration has not been
rigorously studied in COPD. Upon hospitalization, corticosteroids are administered
intravenously in many hospitals. Oral administration is more convenient, though, because
there is no need for intravenous access, less personnel is required for starting and
monitoring therapy, and material costs are smaller.
The investigators hypothesized that oral administration is not inferior to intravenous
administration of prednisolone in the treatment of patients hospitalized for an acute
exacerbation of COPD.
n/a
Allocation: Randomized, Endpoint Classification: Bio-equivalence Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment
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