Chronic Obstructive Pulmonary Disease Clinical Trial
Official title:
Cost-Effectiveness of Lung Volume Reduction Surgery
Lung volume reduction surgery (LVRS) has been advanced as a therapy to significantly improve quality of life in patients with COPD, but to date no controlled studies have evaluated the impact of LVRS.
Background:
Lung volume reduction surgery (LVRS) has been advanced as a therapy to significantly improve
quality of life in patients with COPD, but to date no controlled studies have evaluated the
impact of LVRS.
Objectives:
Evaluate cost-effectiveness of LVRS compared to current therapy for COPD.
Methods:
This is a case control study in which veterans undergoing LVRS at VA Puget Sound Health Care
System (VAPSHCS) are compared to patients with a similar severity of disease at Boise VAMC
who are not undergoing LVRS. Changes in health related quality of life are being evaluated
using three instruments: the SF-36, the St. George�s Respiratory Questionnaire, and the
Quality of Well-Being Scale, the latter to calculate utility associated with different
health states. Costs will be determined using utilization data on outpatient visits,
medications, oxygen use, inpatient days, radiology tests, laboratory tests, and emergency
room visits are being collected for the twelve months before and after surgery. Costs will
be calculated according to VA and community standards.
Status:
Complete.
;
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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