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Altitude Related Illness In Patients With Respiratory Disease

Chronic Obstructive Pulmonary Disease (COPD) Clinical Trial

Official title:
Dexamethasone for Prophylaxis of Acute Mountain Sickness in Patients With Chronic Obstructive Pulmonary Disease Travelling to Altitude

Clinical Trial Summary

Randomized, placebo controlled trial evaluating efficacy of dexamethasone in preventing acute mountain sickness in lowlanders with chronic obstructive lung disease travelling from 700 m to 3200 m.

Clinical Trial Description

This is a randomized, placebo-controlled, double-blind parallel trial evaluating the efficacy of dexamethasone prophylaxis in reducing the incidence of acute mountain sickness in lowlanders with chronic obstructive pulmonary disease travelling to altitude. Participants living in the Bishkek area, Kyrgyzstan (700m), will be transferred by car within 4h to the Tuja Ashu high altitude clinic (3200 m), and stay there for 2 days. Dexamethasone 2x4mg/day (or placebo), will be administered before departure at 700 m and during the stay at altitude. Outcomes will be assessed during the stay at 3200 m. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02450968
Study type Interventional
Source University of Zurich
Contact
Status Completed
Phase Phase 4
Start date May 2015
Completion date December 2015
View Details
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