Chronic Obstructive Pulmonary Disease (COPD) Clinical Trial
Official title:
Effects of Pulmonary Rehabilitation on Computerized Respiratory Sounds in Patients With Chronic Obstructive Pulmonary Disease
The effect of pulmonary rehabilitation in patients with chronic obstructive pulmonary disease
(COPD) has been based on systemic outcome measures, however, little is known about the
effectiveness of this intervention on patients' lung function. The forced expiratory volume
in one second (FEV1), despite of being the gold standard for assessing lung function in COPD,
is poorly responsive to pulmonary rehabilitation. Thus, an objective and responsive outcome
measure to assess the effect of pulmonary rehabilitation on lung function is needed.
Computerized respiratory sounds have been found to be a more sensitive indicator, detecting
and characterizing the severity of respiratory diseases before any other measure, however its
potential to detect changes after pulmonary rehabilitation has never been explored.
Therefore, this study aims to assess the effects of pulmonary rehabilitation on the
characteristics of computerized respiratory sounds in patients with COPD.
A randomized controlled study with one group undergoing pulmonary rehabilitation (n=25) and
other group receiving standard care (n=25) will be conducted. The pulmonary rehabilitation
program will included exercise training (3*week) and psychoeducation (1*week).
Computerized respiratory sounds, lung function, exercise capacity, quadriceps muscle
strength, health-related quality of life and health services use will be assessed in both
groups, at baseline, immediately post-intervention and at follow-ups (3 and 6 months after
PR).
Descriptive and inferential statistics will be used.
It is expected that significant changes occur on the characteristics of computerized
respiratory sounds in patients enrolled in the pulmonary rehabilitation group, in comparison
with patients receiving standard care. Thus, computerized respiratory sounds could provide a
simple, objective and non-invasive measure to assess lung function changes after pulmonary
rehabilitation.
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