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Clinical Trial Summary

Radiofrequency ablation of the genicular nerves using ultrasound is safe and effective for treating intractable knee osteoarthritis pain by using either monopolar or bipolar radiofrequency ablation.

This technique is based on anatomical studies demonstrating that genicular nerves are accompanied by genicular arteries. Ultrasound-guided RF genicular ablation yielded both significant reductions in knee pain and improvements in functional capacity.


Clinical Trial Description

The aim of this study is to compare between ultrasound guided monopolar and bipolar radiofrequency ablation in chronic knee osteoarthritis.

Osteoarthritis of knee joint is one of the most common disease conditions with advanced age and leads to considerable morbidity in terms of pain, stiffness, limitation in functions, disturbance in sleep and psychological disturbance

A diagnostic genicular nerve block (GNB) with local anesthetic is performed before RF genicular ablation, and a successful response to GNB is considered to indicate the need for RF genicular ablation ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04112264
Study type Interventional
Source Mansoura University
Contact Sherif A Mousa, MD
Phone 00201001637298
Email S_abdomousa@yahoo.com
Status Recruiting
Phase N/A
Start date October 4, 2020
Completion date June 1, 2021

See also
  Status Clinical Trial Phase
Enrolling by invitation NCT03379883 - Genicular Nerve and Intra-articular Radiofrequency Versus Platelet Rich Plasma Injection for Knee Osteoarthritis N/A
Recruiting NCT06173830 - Ultrasound-guided Radiofrequency Ablation of the Genicular Nerve Versus Physical Therapy for Chronic Knee Osteoarthritis N/A
Not yet recruiting NCT04751253 - High Intensity Laser and Exercises in Knee OA N/A