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The Effects of Renal Function and Atrial Fibrillation on Lipoproteins and Clot Structure/Function — RALiC  

Atrial Fibrillation Clinical Trial

Official title:
Stratifying Clinical Risk in Patients With Atrial Fibrillation and Chronic Kidney Disease by Studying How Abnormalities in Clot Structure/Function and Lipoproteins Contribute to Thrombosis and Bleeding

Clinical Trial Summary

This study is designed to investigate the role of lipids/lipoproteins as a potential cause for the harmful changes seen in fibrin clot properties with renal dysfunction and atrial fibrillation

Clinical Trial Description

This is a prospective, observational, blinded study that will be conducted in two parts. The first study will assess the relationship between lipids/lipoproteins and fibrin clot properties among anticoagulated atrial fibrillation patients with and without renal dysfunction. The second study will assess the effects of statin therapy on lipids/lipoproteins and fibrin clot properties in anticoagulated atrial fibrillation patients with renal dysfunction. Renal dysfunction is defined as an estimated glomerular filtration rate below 50 ml/min/1.73m2 for the purposes for this trial. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04043026
Study type Observational
Source University of Liverpool
Contact
Status Terminated
Phase
Start date September 26, 2019
Completion date August 1, 2022
View Details
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