Clinical Trial Details
— Status: Not yet recruiting
Administrative data
| NCT number |
NCT04618666 |
| Other study ID # |
Lap appendectomy |
| Secondary ID |
|
| Status |
Not yet recruiting |
| Phase |
N/A
|
| First received |
|
| Last updated |
|
| Start date |
December 2021 |
| Est. completion date |
March 2024 |
Study information
| Verified date |
November 2020 |
| Source |
Assiut University |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Interventional
|
Clinical Trial Summary
comparison between laparoscopic and open appendectomy in the management of chronic
appendicitis
Description:
The appendix is a blind-ended tube connected to the cecum, from which it develops in the
embryo. The most common diseases of the appendix (in humans) are appendicitis and carcinoid
tumors. Appendicitis is inflammation of the appendix. Symptoms commonly include right lower
abdominal pain, nausea, vomiting, and decreased appetite. However, approximately 40% of
people do not have these typical symptoms . Appendicitis is caused by a blockage of the
hollow portion of the appendix. This is most commonly due to a calcified "stone" made of
feces. Inflamed lymphoid tissue from a viral infection, parasites, gallstone, or tumors may
also cause the blockage. This blockage leads to increased pressures in the appendix,
decreased blood flow to the tissues of the appendix, and bacterial growth inside the appendix
causing inflammation. The combination of inflammation, reduced blood flow to the appendix and
distention of the appendix causes tissue injury and tissue death. If this process is left
untreated, the appendix may burst, releasing bacteria into the abdominal cavity, leading to
increased complications. The surgical procedure for the removal of the appendix is called an
appendicectomy. Appendicectomy can be performed through open or laparoscopic surgery. The
surgical procedure for the removal of the appendix is called an appendicectomy .
Appendicectomy can be performed through open or laparoscopic surgery. When the surgeon uses
the open approach, he makes an incision in the lower right section of the abdomen. Most
incisions are less than 3 in (7.6 cm) in length. The surgeon then identifies all of the
organs in the abdomen and examines them for other disease or abnormalities. The appendix is
located and brought up into the wounds. The surgeon separates the appendix from all the
surrounding tissue and its attachment to the cecum, and then removes it. The site where the
appendix was previously attached, the cecum, is closed and returned to the abdomen The muscle
layers and then the skin are sewn together . When the surgeon performs a laparoscopic
appendectomy, four incisions, each about 1 in (2.5 cm) in length, are made. One incision is
near the umbilicus, or navel, and one is between the umbilicus and the pubis. Two other
incisions are smaller and are on the right side of the lower abdomen. The surgeon then passes
a camera and special instruments through these incisions. With the aid of this equipment, the
surgeon visually examines the abdominal organs and identifies the appendix. The appendix is
then freed from all of its attachments and removed. The place where the appendix was formerly
attached, the cecum, is stitched. The appendix is removed through one of the incisions. The
instruments are removed and then all of the incisions are closed . The primary objective of
this study was to compare the laparoscopic approach and the conventional technique in the
treatment of chronic Appendicitis.
