Hypnosis for Chronic Idiopathic Pruritus

Chronic Idiopathic Pruritus Clinical Trial

Official title:

A Prospective Study of Hypnosis for Chronic Idiopathic Pruritus

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04829578
• Other study ID #: 20-AOIP-01
• Secondary ID: 2020-A03263-36
• Status: Completed
• Phase: N/A
• Start date: April 13, 2021
• Est. completion date: October 31, 2022

Study information

• Verified date: January 2024
• Source: Centre Hospitalier Universitaire de Nice
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Chronic idiopathic pruritus (CIP) is a frequent and disabling condition, for which there is no specific treatment. It was shown previously that hypnosis can relieve painful sensations. Pain and pruritus share many similarities regarding sensory receptors and pathways, suggesting that hypnosis might help relief CIP.

Description:

Chronic idiopathic pruritus (CIP) is a frequent and disabling condition, with significative impact on quality of life. At present, there is no specific treatment for CIP. Topical steroids are frequently used, with partial efficacy, and adverse effects. Hypnosis is a specific state of conscience. It differs from waking state, sleeping state, relaxation, or meditation. In this state, the person is highly responsive to suggestion. In medicine, hypnosis can be used to engage the internal resources of the person against unpleasant feelings. It was shown previously that hypnosis can relieve painful sensations. Pain and pruritus share many similarities regarding sensory receptors and pathways, suggesting that hypnosis might help relief CIP.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 12
• Est. completion date: October 31, 2022
• Est. primary completion date: September 13, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

• Male or female of at least 18 years at screening
• Diagnosis of chronic (at least 6 wks.) idiopathic pruritus
• Pruritus Numeric Rating Scale > = 4

Exclusion Criteria:

• Pruritus caused by a dermatological or a systemic conditions
• Suicidal crisis, moderate, or severe
• Psychosis (schizophrenia, persistent delusional disorder)
• Bipolar disorder, not stabilized or decompensating
• Personality disorder, decompensated

Related Conditions & MeSH terms

• Chronic Idiopathic Pruritus
• Pruritus

Intervention

Other:
• Hypnosis
Chronic idiopathic pruritus is treated by hypnosis

Locations

Country	Name	City	State
France	Chu de Nice	Nice

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier Universitaire de Nice

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change From Baseline in Pruritus Numeric Rating Scale	Assessment of the intensity of pruritis in Pruritus Numeric Rating Scal; the minimum and maximum values 0 to 10	Day 84
Secondary	Change From Baseline in Pruritus Verbal Rating Scale	Assessment of Pruritus by pruritus Verbal Rating Scale; the minimum and maximum values 0 to 4	Day 84
Secondary	Change From Baseline in Sleeping Scale	assessment in sleeping scale ; the minimum and maximum values 0 to 10	Day 84
Secondary	Change From Baseline in DLQI scale	assessment in DLQI scale; result between 0 to 30	Day 84
Secondary	Change From Baseline in HAD scale	assessment in HAD scale; result between 0 to 42	Day 84
Secondary	Change From Baseline in usage of topical steroids	assessment in usage of topical steroids	Day 84
Secondary	Evaluation of tolerance of hypnosis	assessment of tolerance of hypnosis with report of adverse event	Day 84