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Clinical Trial Summary

To Identify the collected cases who can stop NAs safely with satisfactory clinical outcome including sustain viral remission and HBsAg clearance among chronic hepatitis B(CHB) patients.


Clinical Trial Description

Nucleos(t)ides analogues(NAs) is a safe and effective treatment among chronic hepatitis B(CHB) patients with excellent tolerance. Entecavir or tenofovir mono therapy has been shown to achieve inhibition of HBV replication in almost all adherent patients. However, HBsAg loss rate is low even after long-term NAs treatment. Recent studies indicated that cessation of NAs treatment could increase HBsAg clearance rate. Identifying the collected cases who can stop NAs safely with satisfactory clinical outcome including sustain viral remission and HBsAg clearance is very important. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03792919
Study type Interventional
Source Humanity & Health Medical Group Limited
Contact George Lau, MD
Phone 852-28613777
Email gkklau@netvigator.com
Status Recruiting
Phase Phase 4
Start date December 1, 2018
Completion date December 31, 2025

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