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Clinical Trial Summary

The objective of this prospective, multicenter controlled study is to assess the feasibility of a patient-tailored implantation by creating a cloud-based pre-procedural multimodality CRT-roadmap by integration of 3D images from 3D activation sequence from ECG, and coronary venous anatomy from cardiac computed tomography. This CRT-roadmap will be used to guide LV lead placement to a coronary vein in an electrically late-activated region. Study Hypothesis: At least 75% of patients undergoing a CRT implantation guided by non-invasive electrical and venous anatomy assessment (XSPLINE technology) will show a reduction of left ventricular end-systolic volume of 15% or more at 6-month evaluation.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05327062
Study type Interventional
Source XSpline S.p.A.
Contact Claudia M Amatruda, PhD
Phone +390471200372
Email amatruda@xspline.com
Status Recruiting
Phase N/A
Start date March 6, 2023
Completion date September 2024

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